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Lipids and lipid derivatives for RNA delivery
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …
diseases through various mechanisms including knockdown of pathological genes …
The landscape of nanoparticle-based siRNA delivery and therapeutic development
Five small interfering RNA (siRNA)-based therapeutics have been approved by the Food
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
Advances in magnetic nanoparticles for biomedical applications
Magnetic nanoparticles (NPs) are emerging as an important class of biomedical functional
nanomaterials in areas such as hyperthermia, drug release, tissue engineering, theranostic …
nanomaterials in areas such as hyperthermia, drug release, tissue engineering, theranostic …
Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Rekindling RNAi therapy: materials design requirements for in vivo siRNA delivery
With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
Nanoparticle-mediated delivery towards advancing plant genetic engineering
Genetic engineering of plants has enhanced crop productivity in the face of climate change
and a growing global population by conferring desirable genetic traits to agricultural crops …
and a growing global population by conferring desirable genetic traits to agricultural crops …
Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy
E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …
Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …
disease in incidence. Despite significant worldwide investment in research, cancer remains …
[HTML][HTML] Nano-scale delivery systems for siRNA delivery in cancer therapy: New era of gene therapy empowered by nanotechnology
N Ebrahimi, MS Manavi, A Nazari, A Momayezi… - Environmental …, 2023 - Elsevier
RNA interference (RNAi) is a unique treatment approach used to decrease a disease's
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …
Engineered nanoparticles for drug delivery in cancer therapy
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …
number of issues associated with conventional therapeutic agents, including their poor …