Pulmonary fibrosis (PF) is a progressive interstitial inflammatory disease with a high
mortality rate. Patients with PF commonly experience a chronic dry cough and progressive …

In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological
processes is overcome and system biology approaches have been providing new …

Exosomal miRNAs play a critical role in cancer biology and could be potential biomarkers
for cancer diagnosis. However, due to the low abundance of miRNAs in the exosomes …

MicroRNAs (miRNAs) in extracellular vesicles (EVs) play essential roles in cancer initiation
and progression. Quantitative measurements of EV miRNAs are critical for cancer diagnosis …

We aimed to investigate whether exosomes (Exo) affected chronic obstructive pulmonary
disease (COPD) by influencing ferroptosis of bronchial epithelial cells (BECs) and the …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3
million people worldwide. Senescence and small extracellular vesicles (sEVs) have been …

Ambient fine particulate matter (PM 2.5) is linked to an increased risk of chronic obstructive
pulmonary disease (COPD) exacerbations, which significantly increase the risk of mortality …

Mitochondria are multitasking organelles involved in maintaining the cell homoeostasis.
Beyond its well-established role in cellular bioenergetics, mitochondria also function as …

Lipids are major actors and regulators of physiological processes within the lung. Initial
research has described their critical role in tissue homeostasis and in orchestrating cellular …

Peritoneal dialysis is an efficient renal replacement therapy for patients with end-stage
kidney disease. However, continuous exposure of the peritoneal membrane to dialysate …