Hepatitis B virus (HBV)-specific CD8+ T cells play a dominant role during acute-resolving
HBV infection but are functionally impaired during chronic HBV infection in humans. These …

Glucose metabolism is essential for the activation, differentiation and function of T cells and
proper glucose metabolism is required to maintain effective T cell immunity. Dysregulation of …

Hepatitis B virus (HBV) is an ancient virus that has evolved unique strategies to persist as a
chronic infection in humans. Here, I summarize the innate and adaptive features of the HBV …

Summary Background and Aims For chronic hepatitis B (CHB) patients, there is still a need
to improve hepatitis B surface antigen (HBsAg) clearance rates. This study aimed to assess …

Hepatitis C virus (HCV) has spread worldwide, and it is responsible for potentially severe
chronic liver disease and primary liver cancer. Chronic infection remains for life if not …

The early and mid-career researchers (EMCRs) of scientific communities represent the
forefront of research and the future direction in which a field takes. The opinions of this key …

Hepatitis B Virus (HBV) infections pose a global public health challenge. Despite extensive
research on this disease, the intricate mechanisms underlying persistent HBV infection …

Objective: Chronic HBV infection (CHB) exhausts HBV-specific T cells, develops epigenetic
imprints that impair immune responses, and limits the effectiveness of immune checkpoint …

Identification and isolation of antigen-specific T cells for downstream transcriptomic analysis
is key for various immunological studies. Traditional methods using major histocompatibility …

Introduction More than 350 million people worldwide live with chronic viral hepatitis and are
thus at risk for severe complications like liver cirrhosis and hepatocellular carcinoma (HCC) …