Emodin is a natural anthraquinone derivative that occurs in many widely used Chinese
medicinal herbs, such as Rheum palmatum, Polygonum cuspidatum and Polygonum …

With the increasing prevalence of untreatable infections caused by antibiotic-resistant
bacteria, the discovery of new drugs from natural products has become a hot research topic …

Our previous studies demonstrated that the natural compound emodin blocks the tumor-
promoting feedforward interactions between cancer cells and macrophages, and thus …

Epstein–Barr virus (EBV), a known tumorigenic virus, is associated with various
neuropathies, including multiple sclerosis (MS). However, there is no anti-EBV FDA …

Many enzymes contain tunnels and gates that are essential to their function. Gates
reversibly switch between open and closed conformations and thereby control the traffic of …

Crocus sativus L. is known in herbal medicine for the various pharmacological effects of its
components, but no data are found in literature about its biological properties toward …

Background Antimicrobial activity of anthraquinone compounds of emodine type has been
reported by many authors. These compounds are found in Vismia laurentii (Clusiaceae), a …

Gastric problems are often caused by the well-known Helicobacter pylori (H. pylori)
bacterium. One of the biggest obstacles to the treatment of H. pylori infections is increasing …

Isothermal titration calorimetry (ITC) is now an established and invaluable method for
determining the thermodynamic constants, association constant and stoichiometry of …

Secondary metabolites are small molecules that show large structural diversity and a broad
range of bioactivities. Some metabolites are attractive as drugs or pigments while others act …