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The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
SARS-CoV-2 variants, spike mutations and immune escape
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
Persistent immune imprinting occurs after vaccination with the COVID-19 XBB. 1.5 mRNA booster in humans
Immune imprinting describes how the first exposure to a virus shapes immunological
outcomes of subsequent exposures to antigenically related strains. Severe acute respiratory …
outcomes of subsequent exposures to antigenically related strains. Severe acute respiratory …
Bat coronaviruses related to SARS-CoV-2 and infectious for human cells
S Temmam, K Vongphayloth, E Baquero, S Munier… - Nature, 2022 - nature.com
The animal reservoir of SARS-CoV-2 is unknown despite reports of SARS-CoV-2-related
viruses in Asian Rhinolophus bats,,–, including the closest virus from R. affinis, RaTG13 …
viruses in Asian Rhinolophus bats,,–, including the closest virus from R. affinis, RaTG13 …
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …
from protection by vaccines and therapeutic antibodies. A key test for potential …
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice
SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial
In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed
for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as …
for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as …
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells
ABSTRACT The novel SARS-CoV-2 Omicron variant (B. 1.1. 529), first found in early
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …
highlighted the need for vaccines that not only prevent disease but also prevent …