Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Photodynamic therapy of cancer: an update

P Agostinis, K Berg, KA Cengel… - CA: a cancer journal …, 2011 - Wiley Online Library
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy

G Chen, I Roy, C Yang, PN Prasad - Chemical reviews, 2016 - ACS Publications
Nanoparticles are generally defined as any particulate material for which at least one
dimension lies in the range of 1− 100 nm. 1− 3 They can exist in various shapes, such as …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Aggregation-induced emission: phenomenon, mechanism and applications

Y Hong, JWY Lam, BZ Tang - Chemical communications, 2009 - pubs.rsc.org
It is textbook knowledge that chromophore aggregation generally quenches light emission.
In this feature article, we give an account on how we observed an opposite phenomenon …

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

NM Idris, MK Gnanasammandhan, J Zhang, PC Ho… - Nature medicine, 2012 - nature.com
Conventional photodynamic therapy (PDT) is limited by the penetration depth of visible light
needed for its activation. Here we used mesoporous-silica–coated upconversion fluorescent …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …