Autophagy and autophagy-related diseases: a review
T Ichimiya, T Yamakawa, T Hirano… - International journal of …, 2020 - mdpi.com
Autophagy refers to the process involving the decomposition of intracellular components via
lysosomes. Autophagy plays an important role in maintaining and regulating cell …
lysosomes. Autophagy plays an important role in maintaining and regulating cell …
ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Causes and consequences of micronuclei
Micronuclei are small membrane-bounded compartments with a DNA content encapsulated
by a nuclear envelope and spatially separated from the primary nucleus. Micronuclei have …
by a nuclear envelope and spatially separated from the primary nucleus. Micronuclei have …
A guide to the regulation of selective autophagy receptors
A Gubas, I Dikic - The FEBS journal, 2022 - Wiley Online Library
Autophagy is a highly conserved catabolic process cells use to maintain their homeostasis
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS
Alterations in the components [nucleoporins (Nups)] and function of the nuclear pore
complex (NPC) have been implicated as contributors to the pathogenesis of genetic forms of …
complex (NPC) have been implicated as contributors to the pathogenesis of genetic forms of …
In-cell architecture of the nuclear pore and snapshots of its turnover
Nuclear pore complexes (NPCs) fuse the inner and outer membranes of the nuclear
envelope. They comprise hundreds of nucleoporins (Nups) that assemble into multiple …
envelope. They comprise hundreds of nucleoporins (Nups) that assemble into multiple …
The nuclear pore complex: birth, life, and death of a cellular behemoth
Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …
[HTML][HTML] A selective autophagy pathway for phase-separated endocytic protein deposits
Autophagy eliminates cytoplasmic content selected by autophagy receptors, which link
cargo to the membrane-bound autophagosomal ubiquitin-like protein Atg8/LC3. Here, we …
cargo to the membrane-bound autophagosomal ubiquitin-like protein Atg8/LC3. Here, we …
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
Autophagic mechanisms that maintain nuclear envelope homoeostasis are bulwarks to
ageing and disease. Here we define a quantitative and ultrastructural timeline of nuclear …
ageing and disease. Here we define a quantitative and ultrastructural timeline of nuclear …