Reversible-deactivation radical polymerization (Controlled/living radical polymerization): From discovery to materials design and applications

N Corrigan, K Jung, G Moad, CJ Hawker… - Progress in Polymer …, 2020‏ - Elsevier
Reversible-deactivation radical polymerization (RDRP) processes, such as atom transfer
radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) …

Polymer–drug conjugate therapeutics: advances, insights and prospects

I Ekladious, YL Colson, MW Grinstaff - Nature reviews Drug discovery, 2019‏ - nature.com
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …

Advanced materials by atom transfer radical polymerization

K Matyjaszewski - Advanced Materials, 2018‏ - Wiley Online Library
Atom transfer radical polymerization (ATRP) has been successfully employed for the
preparation of various advanced materials with controlled architecture. New catalysts with …

From precision polymers to complex materials and systems

JF Lutz, JM Lehn, EW Meijer… - Nature Reviews Materials, 2016‏ - nature.com
Complex chemical systems, such as living biological matter, are highly organized structures
based on discrete molecules in constant dynamic interactions. These natural materials can …

Macromolecular engineering by atom transfer radical polymerization

K Matyjaszewski, NV Tsarevsky - Journal of the American …, 2014‏ - ACS Publications
This Perspective presents recent advances in macromolecular engineering enabled by
ATRP. They include the fundamental mechanistic and synthetic features of ATRP with …

Atom transfer radical polymerization (ATRP): current status and future perspectives

K Matyjaszewski - Macromolecules, 2012‏ - ACS Publications
Current status and future perspectives in atom transfer radical polymerization (ATRP) are
presented. Special emphasis is placed on mechanistic understanding of ATRP, recent …

Therapeutic protein–polymer conjugates: advancing beyond PEGylation

EM Pelegri-O'Day, EW Lin… - Journal of the American …, 2014‏ - ACS Publications
Protein–polymer conjugates are widely used as therapeutics. All Food and Drug
Administration (FDA)-approved protein conjugates are covalently linked to poly (ethylene …

[HTML][HTML] Copper-mediated living radical polymerization (atom transfer radical polymerization and copper (0) mediated polymerization): from fundamentals to …

C Boyer, NA Corrigan, K Jung, D Nguyen… - Chemical …, 2016‏ - ACS Publications
The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …

[PDF][PDF] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020‏ - pure.mpg.de
abstract The conjugation of synthetic polymers with various biomolecules provides an easy
access to biohybrid materials which combine advantages from both the synthetic world and …

Preparation of biomolecule-polymer conjugates by grafting-from using ATRP, RAFT, or ROMP

MS Messina, KMM Messina, A Bhattacharya… - Progress in polymer …, 2020‏ - Elsevier
Biomolecule-polymer conjugates are constructs that take advantage of the functional or
otherwise beneficial traits inherent to biomolecules and combine them with synthetic …