Living Cell-Mediated Self-Assembly: From Monomer Design and Morphology Regulation to Biomedical Applications

C Liu, H Ma, S Yuan, Y **, W Tian - ACS nano, 2025 - ACS Publications
The self-assembly of molecules into highly ordered architectures is a ubiquitous and natural
process, wherein molecules spontaneously organize into large structures to perform diverse …

Nanoarchitectonics for Biomedical Research: Post‐Nanotechnology Materials Approach for Bio‐Active Application

K Ariga - Advanced NanoBiomed Research, 2024 - Wiley Online Library
Nanoarchitectonics, as a post‐nanotechnology concept, represents a methodology for the
construction of functional materials employing atoms, molecules, and nanomaterials as …

Host–Guest Adduct as a Stimuli‐Responsive Prodrug: Enzyme‐Triggered Self‐Assembly Process of a Short Peptide Within Mitochondria to Induce Cell Apoptosis

S Sarkar, A Chatterjee, D Kim, C Saritha… - Advanced …, 2024 - Wiley Online Library
To address the issue of nonspecific biodistribution of a chemotherapeutic drug, stable [2]
pseudorotaxane complexes (PK@ CAOPP and PR@ CAOPP) are used to demonstrate a …

Enzyme-instructed intramitochondrial polymerization for enhanced anticancer treatment without the development of drug-resistance

S Kim, Y Lee, MS Seu, Y Sim, JH Ryu - Journal of Controlled Release, 2024 - Elsevier
Intracellular polymerization in living cells motivated chemists to generate polymeric
structures with a multitude of possibilities to interact with biomacromolecules. However, out …

Folic Acid-Functionalized β-Cyclodextrin for Delivery of Organelle-Targeted Peptide Chemotherapeutics in Cancer

HW Ok, S **, G Park, B Jana, JH Ryu - Molecular Pharmaceutics, 2024 - ACS Publications
Recent emphasis on the design of drug delivery systems typically involves the effective
transport of a pharmaceutical substance to the disease site with the desired therapeutic …

Artificial Polymerizations in Living Organisms for Biomedical Applications

Y Chen, BSN Tan, Y Cheng… - Angewandte Chemie …, 2024 - Wiley Online Library
Within living organisms, numerous nanomachines are constantly involved in complex
polymerization processes, generating a diverse array of biomacromolecules for maintaining …

[HTML][HTML] Organelle Targeting Self-Assembled Fluorescent Probe for Anticancer Treatment

MS Hasan, S Kim, C Lim, J Lee, MS Seu, JH Ryu - Chemosensors, 2024 - mdpi.com
Organic fluorescent probes have attracted attention for bioimaging due to their advantages,
including high sensitivity, biocompatibility, and multi-functionality. However, some limitations …