Among the many neuromodulators used by the mammalian brain to regulate circuit function
and plasticity, dopamine (DA) stands out as one of the most behaviorally powerful …

The basal ganglia are a chain of subcortical nuclei that facilitate action selection. Two striatal
projection systems—so-called direct and indirect pathways—form the functional backbone of …

Dopamine is involved in physiological processes like learning and memory, motor control
and reward, and pathological conditions such as Parkinson's disease and addiction. In …

Missale, Cristina, S. Russel Nash, Susan W. Robinson, Mohamed Jaber, and Marc G.
Caron. Dopamine Receptors: From Structure to Function. Physiol. Rev. 78: 189–225, 1998 …

Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

Dopamine shapes a wide variety of psychomotor functions. This is mainly accomplished by
modulating cortical and thalamic glutamatergic signals im**ing upon principal medium …

The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …

The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has
shared signaling properties that contribute to the definition of the receptor class, although …

Dopamine (DA) is one of the major neurotransmitters and participates in a number of
functions such as motor coordination, emotions, memory, reward mechanism …

Dopamine (DA) depletion in the basal ganglia (BG) of Parkinson's patients gives rise to both
frontal-like and implicit learning impairments. Dopaminergic medication alleviates some …