Retinoblastoma
Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …
[HTML][HTML] Update on pathology of retinoblastoma
Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which
maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor …
maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor …
High-risk retinoblastoma based on international classification of retinoblastoma: analysis of 519 enucleated eyes
PURPOSE: To determine the correlation between the International Classification of
Retinoblastoma (ICRB) and histopathologic high-risk retinoblastoma. DESIGN …
Retinoblastoma (ICRB) and histopathologic high-risk retinoblastoma. DESIGN …
Clinical features predictive of high-risk retinoblastoma in 403 Asian Indian patients: a case-control study
Purpose To identify the clinical features predictive of high-risk retinoblastoma on
histopathology. Design Case-control study. Participants A total of 145 cases with …
histopathology. Design Case-control study. Participants A total of 145 cases with …
SIOP‐PODC recommendations for graduated‐intensity treatment of retinoblastoma in develo** countries
G Chantada, S Luna‐Fineman… - Pediatric Blood & …, 2013 - Wiley Online Library
Retinoblastoma remains incurable in many regions of the world. The major obstacles to cure
are delayed diagnosis, poor treatment compliance, and lack of evidence‐based …
are delayed diagnosis, poor treatment compliance, and lack of evidence‐based …
Defining high-risk retinoblastoma: a multicenter global survey
S Kaliki, CL Shields, N Cassoux, FL Munier… - JAMA …, 2022 - jamanetwork.com
Importance High-risk histopathologic features of retinoblastoma are useful to assess the risk
of systemic metastasis. In this era of globe salvage treatments for retinoblastoma, the …
of systemic metastasis. In this era of globe salvage treatments for retinoblastoma, the …
Retinoblastoma. Fifty years of progress. The LXXI Edward Jackson memorial lecture
HE Grossniklaus - American journal of ophthalmology, 2014 - Elsevier
Purpose To review the progress made in understanding the genetic basis, molecular
pathology, and treatment of retinoblastoma since the previous Jackson lecture on the topic …
pathology, and treatment of retinoblastoma since the previous Jackson lecture on the topic …
PDGF, NGF, and EGF as main contributors to tumorigenesis in high-risk retinoblastoma
Retinoblastoma (RB) is the most common form of eye cancer experienced in childhood. Its
aggressive malignancy is associated with excellent survival rates in high-income countries; …
aggressive malignancy is associated with excellent survival rates in high-income countries; …
Disparities in retinoblastoma presentation, treatment, and outcomes in developed and less-developed countries
G Singh, AB Daniels - Seminars in Ophthalmology, 2016 - Taylor & Francis
Retinoblastoma (RB) is the most common intraocular malignancy in children. In the past
century, RB survival rates in developed countries (DCs) have improved from< 5% to as high …
century, RB survival rates in developed countries (DCs) have improved from< 5% to as high …
Histopathologic grading of anaplasia in retinoblastoma
Purpose To determine whether the degree of tumor anaplasia has prognostic value by
evaluating its correlation with high-risk histopathologic features and clinical outcomes in a …
evaluating its correlation with high-risk histopathologic features and clinical outcomes in a …