Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Despite the comprehensive applications in bioimaging, biosensing, drug/gene delivery, and
tumor therapy of manganese oxide nanomaterials (MONs including MnO2, MnO, Mn2O3 …

Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells
by converting endogenous H2O2 into the highly toxic hydroxyl radical (. OH). There is a …

Reactive oxygen species (ROS)-induced apoptosis is a promising treatment strategy for
malignant neoplasms. However, current systems are highly dependent on oxygen status …

In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …

The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …

Poor O2 supply to the infiltrated immune cells in the joint synovium of rheumatoid arthritis
(RA) up-regulates hypoxia-inducible factor (HIF-1α) expression and induces reactive oxygen …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …