Bioactive potential of natural biomaterials: Identification, retention and assessment of biological properties

K Joyce, GT Fabra, Y Bozkurt, A Pandit - Signal transduction and …, 2021 - nature.com
Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

[HTML][HTML] Hyaluronic acid in the third millennium

A Fallacara, E Baldini, S Manfredini, S Vertuani - Polymers, 2018 - mdpi.com
Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of
research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide …

[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

Embedded bioprinting of breast tumor cells and organoids using low‐concentration collagen‐based bioinks

W Shi, S Mirza, M Kuss, B Liu, A Hartin… - Advanced …, 2023 - Wiley Online Library
Bioinks for 3D bioprinting of tumor models should not only meet printability requirements but
also accurately maintain and support phenotypes of tumor surrounding cells to recapitulate …

[HTML][HTML] Advanced functional chitosan-based nanocomposite materials for performance-demanding applications

Y Guo, D Qiao, S Zhao, B Zhang, F **e - Progress in Polymer Science, 2024 - Elsevier
Chitosan holds great promise for demanding applications such as functional packing and
biomedical uses. There has been a notable increase in interest in combining chitosan or its …

Chemical modification of hyaluronan and their biomedical applications

V Hintze, M Schnabelrauch, S Rother - Frontiers in Chemistry, 2022 - frontiersin.org
Hyaluronan, the extracellular matrix glycosaminoglycan, is an important structural
component of many tissues playing a critical role in a variety of biological contexts. This …

A whole-course-repair system based on ROS/glucose stimuli-responsive EGCG release and tunable mechanical property for efficient treatment of chronic periodontitis …

Q Feng, M Zhang, G Zhang, H Mei, C Su… - Journal of Materials …, 2024 - pubs.rsc.org
Elevated glucose levels, multiple pro-inflammatory cytokines and the generation of
excessive reactive oxygen species (ROS) are pivotal characteristics within the …

Fabrication of versatile dynamic hyaluronic acid-based hydrogels

W Shi, B Hass, MA Kuss, H Zhang, S Ryu, D Zhang… - Carbohydrate …, 2020 - Elsevier
In this study, an injectable and self-healing hydrogel based on the boronic ester dynamic
covalent bond between phenylboronic acid modified hyaluronic acid (HA-PBA) and the …

[HTML][HTML] Hyaluronic acid: A review of the drug delivery capabilities of this naturally occurring polysaccharide

C Buckley, EJ Murphy, TR Montgomery, I Major - Polymers, 2022 - mdpi.com
The inclusion of physiologically active molecules into a naturally occurring polymer matrix
can improve the degradation, absorption, and release profile of the drug, thus boosting the …

Controlled release of MSC-derived small extracellular vesicles by an injectable Diels-Alder crosslinked hyaluronic acid/PEG hydrogel for osteoarthritis improvement

Y Yang, Z Zhu, R Gao, J Yuan, J Zhang, H Li, Z **e… - Acta biomaterialia, 2021 - Elsevier
Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) show great
therapeutic potential for osteoarthritis (OA). However, their low bioavailability through …