Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection

A Zhang, HD Stacey, MR D'Agostino, Y Tugg… - Nature Reviews …, 2023 - nature.com
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

Treatments for COVID-19

HS Andrews, JD Herman… - Annual review of medicine, 2024 - annualreviews.org
The treatment for COVID-19 has evolved rapidly since the start of the pandemic and now
consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir …

ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19

P Kaplonek, D Cizmeci, G Kwatra, A Izu, JSL Lee… - Nature …, 2023 - nature.com
Despite the success of COVID-19 vaccines, severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants of concern have emerged that can cause breakthrough infections …

Adenoviral-vectored next-generation respiratory mucosal vaccines against COVID-19

S Afkhami, A Kang, V Jeyanathan, Z **ng… - Current Opinion in …, 2023 - Elsevier
The world is in need of next-generation COVID-19 vaccines. Although first-generation
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …

Antibody Fc receptor binding and T cell responses to homologous and heterologous immunization with inactivated or mRNA vaccines against SARS-CoV-2

CA Cohen, NHL Leung, P Kaewpreedee… - Nature …, 2024 - nature.com
Whole virion inactivated vaccine CoronaVac (C) and Spike (S) mRNA BNT162b2 (B)
vaccines differ greatly in their ability to elicit neutralizing antibodies but have somewhat …

Efficacy of combined COVID-19 convalescent plasma with oral RNA-dependent RNA polymerase inhibitor treatment versus neutralizing monoclonal antibody therapy …

T Siripongboonsitti, N Nontawong… - Microbiology …, 2023 - journals.asm.org
The effectiveness of neutralizing monoclonal antibodies against emerging variants with
spike protein mutations has been limited. Early high-titer convalescent plasma therapy …

Association between COVID-19 convalescent plasma antibody levels and COVID-19 outcomes stratified by clinical status at presentation

H Park, C Yu, L Pirofski, H Yoon, D Wu, Y Li… - BMC infectious …, 2024 - Springer
Background There is a need to understand the relationship between COVID-19
Convalescent Plasma (CCP) anti-SARS-CoV-2 IgG levels and clinical outcomes to optimize …

AT cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection

S Boulton, J Poutou, R Gill, N Alluqmani, X He… - … Therapy Methods & …, 2023 - cell.com
SARS-CoV-2, the etiological agent behind the coronavirus disease 2019 (COVID-19)
pandemic, has continued to mutate and create new variants with increased resistance …

Treatment of chronic COVID‐19 with convalescent/postvaccination plasma in patients with hematologic malignancies

M Janssen, A Leo, C Wolf, M Stenzinger… - … journal of cancer, 2024 - Wiley Online Library
Immunocompromised patients are at high risk to fail clearance of SARS‐CoV‐2. Prolonged
COVID‐19 constitutes a health risk and a management problem as cancer treatments often …

Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …

L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …