Fibroblast growth factor (FGF) signaling pathways are essential regulators of vertebrate
skeletal development. FGF signaling regulates development of the limb bud and formation of …

Craniosynostosis is a condition of complex etiology that always involves the premature
fusion of one or multiple cranial sutures and includes various anomalies of the soft and hard …

Craniosynostosis, a condition that includes the premature fusion of one or multiple cranial
sutures, is a relatively common birth defect in humans and the second most common …

Recent studies have shown how volumetric imaging and morphometrics can add
significantly to our understanding of morphogenesis, the developmental basis for variation …

Fibroblast growth factors (FGFs) and their receptors (FGFRs) are expressed throughout all
stages of skeletal development. In the limb bud and in cranial mesenchyme, FGF signaling …

Craniofacial development depends on formation and maintenance of sutures between
bones of the skull. In sutures, growth occurs at osteogenic fronts along the edge of each …

Syndromic craniosynostosis (CS) patients exhibit early, bony fusion of calvarial sutures and
cranial synchondroses, resulting in craniofacial dysmorphology. In this study, we …

Facial sutures contribute significantly to postnatal facial development, but their potential role
in craniofacial disease is understudied. Since interest in their development and physiology …

The cranial endo and dermal skeletons, which comprise the vertebrate skull, evolved
independently over 470 million years ago and form separately during embryogenesis. In …

Fibroblast growth factor receptor 2 (FGFR2) in craniofacial bones mediates osteoprogenitor
proliferation, differentiation, and apoptosis. The distortion of proper craniofacial bone growth …