Targeting endogenous hydrogen peroxide at bone defects promotes bone repair

J Li, F Han, J Ma, H Wang, J Pan… - Advanced functional …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) plays a critical role in tissue repair, including bone.
Therefore, detecting and regulating ROS is essential for monitoring and facilitating bone …

Advances of cobalt nanomaterials as anti-infection agents, drug carriers, and immunomodulators for potential infectious disease treatment

Y Ma, W Lin, Y Ruan, H Lu, S Fan, D Chen, Y Huang… - Pharmaceutics, 2022 - mdpi.com
Infectious diseases remain the most serious public health issue, which requires the
development of more effective strategies for infectious control. As a kind of ultra-trace …

[HTML][HTML] The Effects of the Addition of Strontium on the Biological Response to Calcium Phosphate Biomaterials: A Systematic Review

J Alves Côrtes, J Dornelas, F Duarte, MR Messora… - Applied Sciences, 2024 - mdpi.com
Strontium is known for enhancing bone metabolism, osteoblast proliferation, and tissue
regeneration. This systematic review aimed to investigate the biological effects of strontium …

[HTML][HTML] Neddylation suppression by a macrophage membrane-coated nanoparticle promotes dual immunomodulatory repair of diabetic wounds

R Zeng, B Lv, Z Lin, X Chu, Y **ong, S Knoedler… - Bioactive Materials, 2024 - Elsevier
Oxidative stress, infection, and vasculopathy caused by hyperglycemia are the main barriers
for the rapid repair of foot ulcers in patients with diabetes mellitus (DM). In recent times, the …

Preparation of Compound Salvia miltiorrhizaBlumea balsamifera Nanoemulsion Gel and Its Effect on Hypertrophic Scars in the Rabbit Ear Model

T Chen, Z Wang, X Gong, J Zhang… - Molecular …, 2024 - ACS Publications
Hypertrophic scars (HS) still remain an urgent challenge in the medical community.
Traditional Chinese medicine (TCM) has unique advantages in the treatment of HS …

[HTML][HTML] Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo

Z Liu, H Liu, R Vowden, L Hughes, D Qi… - Journal of Orthopaedic …, 2023 - Elsevier
Background The mixture of different metallic nanoparticles released from intended and
unintended wearing of orthopaedic implants such as the Co/Cr cup and head, Co/Cr sleeves …

Mechanical properties and biocompatibility characterization of 3D printed collagen type II/silk fibroin/hyaluronic acid scaffold

L Gao, Y Li, G Liu, X Lin, Y Tan, J Liu, R Li… - Journal of Biomaterials …, 2024 - Taylor & Francis
Damage to articular cartilage is irreversible and its ability to heal is minimal. The
development of articular cartilage in tissue engineering requires suitable biomaterials as …

Multifunctional barrier membranes promote bone regeneration by scavenging H2O2, generating O2, eliminating inflammation, and regulating immune response

S Liu, H Yang, L Zhang, A Bianco, B Ma… - Colloids and Surfaces B …, 2023 - Elsevier
The injured bone microenvironment is typically characterized by high-level reactive oxygen
species (ROS, mainly H 2 O 2) and low content of oxygen. The former can cause cell …

Exploring NLRP3-related phenotypic fingerprints in human macrophages using Cell Painting assay

M Herring, E Särndahl, O Kotlyar, N Scherbak… - iScience, 2025 - cell.com
Existing research has proven difficult to understand the interplay between upstream
signaling events during NLRP3 inflammasome activation. Additionally, events downstream …

The Effect of Cancer Cell-Derived Exosomal Proteins on Macrophage Polarization: An In-depth Review

K Wadhonkar, S Das, R Subramanian, MH Sk… - Experimental Cell …, 2024 - Elsevier
Background: Cancer is characterized by unregulated cell proliferation, enabling it to invade
and spread to different organs and tissues in the body. Cancer progression is intricately …