Cocaine addiction is a chronic brain disease in which the drug seeking habits and profound
cognitive, emotional and motivational alterations emerge from drug-induced …

Abstract Ethnopharmacological relevance Radix Bupleuri, also named “Chaihu” in Chinese,
is a substance derived from the dry roots of Bupleurum chinense DC.[Apiaceae] and …

After discovering that addictive drugs alter adult neurogenesis, the potential role of adult-
born hippocampal neurons in drug addiction has become a promising research field, in …

Numerous studies have examined links between postnatal neurogenesis and depression
using a range of experimental methods to deplete neurogenesis. The antimitotic drug …

Maternal sleep disturbance in pregnancy causes cognitive impairments and emotional
disorders in offspring. Microglia-mediated inflammatory processes contribute to prenatal …

The administration of cannabidiol has shown promising evidence in the treatment of some
neuropsychiatric disorders, including cocaine addiction. However, little information is …

Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …

Drugs of abuse promote a potent immune response in central nervous system (CNS) via the
activation of microglia and astrocytes. However, the molecular mechanisms underlying …

Although the functional role for newborn neurons in neural circuits is still matter of
investigation, there is no doubt that neurogenesis modulates learning and memory in …

Cannabidiol (CBD) is a potential treatment to decrease the rewarding properties of
psychostimulants. However, the exact mechanism and distinct neuroanatomical areas …