A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis

E Castilla-Ortega, A Serrano, E Blanco, P Araos… - Neuroscience & …, 2016 - Elsevier
Cocaine addiction is a chronic brain disease in which the drug seeking habits and profound
cognitive, emotional and motivational alterations emerge from drug-induced …

Saikosaponin a activates tet1/dll3/notch1 signalling and promotes hippocampal neurogenesis to improve depression-like behavior in mice

Y Tong, G Zhao, R Shuang, H Wang, N Zeng - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Radix Bupleuri, also named “Chaihu” in Chinese,
is a substance derived from the dry roots of Bupleurum chinense DC.[Apiaceae] and …

In the pursuit of new social neurons. Neurogenesis and social behavior in mice: A systematic review

L García-Gómez, I Castillo-Fernández… - Frontiers in Cell and …, 2022 - frontiersin.org
Social behaviors have become more relevant to our understanding of the human nervous
system because relationships with our peers may require and modulate adult neurogenesis …

Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression

M Egeland, C Guinaudie, A Du Preez… - Translational …, 2017 - nature.com
Numerous studies have examined links between postnatal neurogenesis and depression
using a range of experimental methods to deplete neurogenesis. The antimitotic drug …

The inhibitory effect of cannabidiol on the rewarding properties of methamphetamine in part mediates by interacting with the hippocampal D1-like dopamine receptors

M Mohammadi, K Eskandari, R Azizbeigi… - Progress in Neuro …, 2023 - Elsevier
Cannabidiol (CBD) is a potential treatment to decrease the rewarding properties of
psychostimulants. However, the exact mechanism and distinct neuroanatomical areas …

The pharmacological reduction of hippocampal neurogenesis attenuates the protective effects of cannabidiol on cocaine voluntary intake

MÁ Luján, L Cantacorps, O Valverde - Addiction biology, 2020 - Wiley Online Library
The administration of cannabidiol has shown promising evidence in the treatment of some
neuropsychiatric disorders, including cocaine addiction. However, little information is …

Pioglitazone alleviates maternal sleep deprivation-induced cognitive deficits in male rat offspring by enhancing microglia-mediated neurogenesis

Y Han, J Wang, Q Zhao, X **e, R Song, Y **ao… - Brain, Behavior, and …, 2020 - Elsevier
Maternal sleep disturbance in pregnancy causes cognitive impairments and emotional
disorders in offspring. Microglia-mediated inflammatory processes contribute to prenatal …

Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult …

D Ladron de Guevara-Miranda… - Disease models & …, 2017 - journals.biologists.com
Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …

[HTML][HTML] Inhibiting constitutive neurogenesis compromises long-term social recognition memory

AR Pereira-Caixeta, LO Guarnieri, DC Medeiros… - Neurobiology of learning …, 2018 - Elsevier
Although the functional role for newborn neurons in neural circuits is still matter of
investigation, there is no doubt that neurogenesis modulates learning and memory in …

Lysophosphatidic acid‐induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine‐contextual memory

D Ladrón de Guevara‐Miranda… - Addiction …, 2019 - Wiley Online Library
Erasing memories of cocaine–stimuli associations might have important clinical implications
for addiction therapy. Stimulating hippocampal plasticity by enhancing adult hippocampal …