Role of the microbiome in human development

MG Dominguez-Bello, F Godoy-Vitorino, R Knight… - Gut, 2019 - gut.bmj.com
The host-microbiome supraorganism appears to have coevolved and the unperturbed
microbial component of the dyad renders host health sustainable. This coevolution has likely …

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - journals.asm.org
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

Functional effects of human milk oligosaccharides (HMOs)

M Dinleyici, J Barbieur, EC Dinleyici, Y Vandenplas - Gut Microbes, 2023 - Taylor & Francis
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …

[HTML][HTML] Bifidobacteria-mediated immune system imprinting early in life

BM Henrick, L Rodriguez, T Lakshmikanth, C Pou… - Cell, 2021 - cell.com
Immune-microbe interactions early in life influence the risk of allergies, asthma, and other
inflammatory diseases. Breastfeeding guides healthier immune-microbe relationships by …

Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism

T Vatanen, KS Jabbar, T Ruohtula, J Honkanen… - Cell, 2022 - cell.com
The perinatal period represents a critical window for cognitive and immune system
development, promoted by maternal and infant gut microbiomes and their metabolites. Here …

[HTML][HTML] The human microbiome and child growth–first 1000 days and beyond

RC Robertson, AR Manges, BB Finlay… - Trends in …, 2019 - cell.com
The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

Mother's milk: a purposeful contribution to the development of the infant microbiota and immunity

K Le Doare, B Holder, A Bassett… - Frontiers in …, 2018 - frontiersin.org
Breast milk is the perfect nutrition for infants, a result of millions of years of evolution. In
addition to providing a source of nutrition, breast milk contains a diverse array of microbiota …

Gut biogeography of the bacterial microbiota

GP Donaldson, SM Lee, SK Mazmanian - Nature Reviews Microbiology, 2016 - nature.com
Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling

C Jian, P Luukkonen, H Yki-Järvinen, A Salonen… - PloS one, 2020 - journals.plos.org
The use of relative abundance data from next generation sequencing (NGS) can lead to
misinterpretations of microbial community structures, as the increase of one taxon leads to …

Factors affecting early-life intestinal microbiota development

Y Vandenplas, VP Carnielli, J Ksiazyk, MS Luna… - Nutrition, 2020 - Elsevier
Objectives: This paper reviews the published evidence on early-life intestinal microbiota
development, as well as the different factors influencing its development before, at, and after …