Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …

Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

Base pairing RNAs modulate gene expression in all studied organisms. In many bacteria,
the base pairing between most small regulatory RNAs (sRNAs) and their targets is mediated …

The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

Small RNAs (sRNAs) associated with the RNA chaperon protein Hfq are key
posttranscriptional regulators of gene expression in bacteria. Deciphering the sRNA-target …

Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

The IntaRNA algorithm enables fast and accurate prediction of RNA–RNA hybrids by
incorporating seed constraints and interaction site accessibility. Here, we introduce …

Gram-negative bacteria decorate their outermost surface structure, lipopolysaccharide, with
elaborate chemical moieties, which effectively disguises them from immune surveillance and …

The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …

Antibiotic resistance among pathogenic bacteria is an ever-increasing issue worldwide.
Unfortunately, very little has been achieved in the pharmaceutical industry to combat this …