Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency

MI Simone, A Wood, D Campkin, MJ Kiefel… - European Journal of …, 2022 - Elsevier
This review covers the literature in the past 15 years on glycosidase inhibitors lacking a
basic nitrogen (for example iminosugars/azasugars) with a focus on natural terpenoids, and …

Novel 1, 2, 3-triazole compounds: Synthesis, In vitro xanthine oxidase inhibitory activity, and molecular docking studies

A Tan - Journal of Molecular Structure, 2020 - Elsevier
Abstract In this study, novel 1, 2, 3-triazole compounds containing carbasugar frameworks (5
and 6) were synthesized by the copper-catalyzed azide-alkyne cycloaddition reactions and …

Current synthetic approaches to the synthesis of carbasugars from non-carbohydrate sources

A Zorin, L Klenk, T Mack, HP Deigner… - Topics in Current …, 2022 - Springer
Carbasugars are a group of carbohydrate derivatives in which the ring oxygen is replaced
by a methylene group, producing a molecule with a nearly identical structure but highly …

[HTML][HTML] Heparan sulfate, mucopolysaccharidosis IIIB and sulfur metabolism disorders

M Kaczor-Kamińska, K Kamiński, M Wróbel - Antioxidants, 2022 - mdpi.com
Mucopolysaccharidosis, type IIIB (MPS IIIB) is a rare disease caused by mutations in the N-
alpha-acetylglucosaminidase (NAGLU) gene resulting in decreased or absent enzyme …

Chemoselective Nozaki–Hiyama–Takai–Kishi and Grignard reaction: short synthesis of some carbahexopyranoses

A Vinaykumar, B Surender, BV Rao - RSC advances, 2023 - pubs.rsc.org
A common, divergent, efficient, stereoselective and short approach for the total syntheses of
some carbahexopyranoses namely, MK7607,(−)-gabosine A,(−)-conduritol E,(−)-conduritol …

Diverse Library of 5a-Substituted Carba-Glucosamines

B Silkenath, D Kläge, P Eppelin… - The Journal of …, 2024 - ACS Publications
Carba-sugars─ carbohydrate mimics in which the ring oxygen is replaced by a methylene
group─ are carbohydrate analogues of natural or synthetic origin that can have important …

Application of a tandem seleno-michael/aldol reaction in the total syntheses of (+)-Pericosine B,(+)-Pericosine C,(+)-COTC and 7-chloro-analogue of (+)-Gabosine C

N Biduś, P Banachowicz, S Buda - Tetrahedron, 2020 - Elsevier
Abstract Synthesis of (+)-Pericosine B,(+)-Pericosine C,(+)-COTC and a 7-chloro-analogue
of (+)-Gabosine C was achieved via tandem seleno-Michael/aldol reactions as key steps …

General strategy for the synthesis of unsaturated carbasugars via a diastereoselective seleno-Michael/aldol reaction

P Banachowicz, S Buda - RSC advances, 2025 - pubs.rsc.org
Carbasugars are a diverse group of carbohydrate mimetics in which the ring oxygen is
replaced by a methylene group. We have developed a simple and efficient carbasugar …

Synergy of R-(–) carvone and cyclohexenone-based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation

O Riester, P Burkhardtsmaier, Y Gurung, S Laufer… - Scientific Reports, 2022 - nature.com
The widespread use of antibiotics in recent decades has been a major factor in the
emergence of antibiotic resistances. Antibiotic-resistant pathogens pose increasing …

[PDF][PDF] Oliver Riester1, 2, Pia Burkhardtsmaier1, Yuna Gurung1, Stefan Laufer2, 3

HP Deigner, MS Schmidt - Scientific Reports, 2022 - researchgate.net
The widespread use of antibiotics in recent decades has been a major factor in the
emergence of antibiotic resistances. Antibiotic‑resistant pathogens pose increasing …