[HTML][HTML] Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological …

S Paul, S Chakraborty, U Anand, S Dey… - Biomedicine & …, 2021 - Elsevier
Abstract Withania somnifera (L.) Dunal (Solanaceae) has been used as a traditional
Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative …

[HTML][HTML] Withania somnifera L.: Insights into the phytochemical profile, therapeutic potential, clinical trials, and future prospective

S Saleem, G Muhammad, MA Hussain… - Iranian journal of …, 2020 - ncbi.nlm.nih.gov
Withania somnifera L. is a multipurpose medicinal plant of family Solanaceae occurring
abundantly in sub-tropical regions of the world. The folk healers used the plant to treat …

Natural withanolides: an overview

LX Chen, H He, F Qiu - Natural product reports, 2011 - pubs.rsc.org
Covering: August 1996 to March 2010 Withanolides are a group of naturally occurring C28
steroids built on an ergostane skeleton functionalized at carbons 1, 22 and 26, commonly …

Comprehensive metabolic fingerprinting of Withania somnifera leaf and root extracts

S Chatterjee, S Srivastava, A Khalid, N Singh… - Phytochemistry, 2010 - Elsevier
Profiling of metabolites is a rapidly expanding area of research for resolving metabolic
pathways. Metabolic fingerprinting in medicinally important plants is critical to establishing …

Chemical Composition, Biological Activity, and Health‐Promoting Effects of Withania somnifera for Pharma‐Food Industry Applications

J Sharifi-Rad, C Quispe, SA Ayatollahi… - Journal of Food …, 2021 - Wiley Online Library
The Withania genus comes from the Solanaceae family and includes around 23 species,
spread over some areas of the Mediterranean, Asia, and East Africa. Widely used in …

Withanolides from Withania somnifera roots

L Misra, P Mishra, A Pandey, RS Sangwan… - Phytochemistry, 2008 - Elsevier
Two new and seven known withanolides along with β-sitosterol, stigmasterol, β-sitosterol
glucoside, stigmasterol glucoside, α+ β glucose were isolated from the roots of Withania …

Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection

ND Chaurasiya, GC Uniyal, P Lal… - … Journal of Plant …, 2008 - Wiley Online Library
A reversed‐phase HPLC method for the simultaneous analysis of nine structurally similar
withanolides, namely, 27‐hydroxy withanone, 17‐hydroxy withaferin A, 17‐hydroxy‐27 …

Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through …

C Mandal, A Dutta, A Mallick, S Chandra, L Misra… - Apoptosis, 2008 - Springer
Withaferin A (WA) is present abundantly in Withania somnifera, a well-known Indian
medicinal plant. Here we demonstrate how WA exhibits a strong growth-inhibitory effect on …

A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway …

N Dhar, S Razdan, S Rana, WW Bhat… - Frontiers in plant …, 2015 - frontiersin.org
Withania somnifera, a multipurpose medicinal plant is a rich reservoir of pharmaceutically
active triterpenoids that are steroidal lactones known as withanolides. Though the plant has …

Withanolides and related steroids

RI Misico, VE Nicotra, JC Oberti, G Barboza… - Progress in the …, 2011 - Springer
Since the isolation of the first withanolides in the mid-1960s, over 600 new members of this
group of compounds have been described, with most from genera of the plant family …