[HTML][HTML] The evolving role of investigative toxicology in the pharmaceutical industry

F Pognan, M Beilmann, H Boonen, A Czich… - Nature reviews drug …, 2023 - nature.com
For decades, preclinical toxicology was essentially a descriptive discipline in which
treatment-related effects were carefully reported and used as a basis to calculate safety …

Towards modern-age advanced sensors for the management of neurodegenerative disorders: current status, challenges and prospects

A Gautam - ECS Sensors Plus, 2022 - iopscience.iop.org
Neurodegenerative diseases (NDD) are progressive degenerative disorders of the
neurological system with significant social impact worldwide. Their detection at the initial …

Artificial olfactory biohybrid system: an evolving sense of smell

C Qin, Y Wang, J Hu, T Wang, D Liu, J Dong… - Advanced …, 2023 - Wiley Online Library
The olfactory system can detect and recognize tens of thousands of volatile organic
compounds (VOCs) at low concentrations in complex environments. Bioelectronic nose (B …

[HTML][HTML] Nanobiosensors for detection of opioids: A review of latest advancements

M Razlansari, F Ulucan-Karnak, M Kahrizi… - European Journal of …, 2022 - Elsevier
Opioids are generally used as analgesics in pain treatment. Like many drugs, they have side
effects when overdosed and can cause addiction problems. Illegal drug use and misuse are …

Recent advances in functional bismuth chalcogenide nanomaterials: Cancer theranostics, antibacterial and biosensing

Q Wang, J Du, R Ouyang, B Liu, Y Miao, Y Li - Coordination Chemistry …, 2023 - Elsevier
In recent years, the research of bismuth chalcogenide (Bi 2 X 3, X= O, S, Se, and Te)
nanomaterials has expanded from the fields of optics, chemical, and electronic engineering …

Novel and efficient techniques in the discovery of antioxidant peptides

Y Zhang, Y Li, T Ren, P **ao, J Duan - Critical Reviews in Food …, 2024 - Taylor & Francis
As a research hotspot in food science and nutrition, antioxidant peptides can function by
scavenging free radicals, inhibiting peroxides, and chelating metal ions. Therefore, how to …

Using graphene field-effect transistors for real-time monitoring of dynamic processes at sensing interfaces. Benchmarking performance against surface plasmon …

J Scotto, AL Cantillo, E Piccinini… - ACS Applied …, 2022 - ACS Publications
Graphene field-effect transistors (gFETs) are promising tools for the development of precise
and affordable techniques for the study of molecular binding kinetics, crucial in applications …

Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique

Y Qin, Y Yan, J Zhou, X Gao, L Zhao, X Guan - TrAC Trends in Analytical …, 2024 - Elsevier
Natural products have been a significant source of lead compounds in modern drug
discovery. Compared to traditional techniques for active ingredient screening, affinity-based …

Enhancing the performance of photonic sensor using machine-learning approach

YS Dwivedi, R Singh, AK Sharma… - IEEE Sensors …, 2022 - ieeexplore.ieee.org
This article reports on the implementation of adequate machine-learning (ML) models on
different datasets vis-a-vis fiber-optic plasmonic sensor devices. The variation of the sensor's …

Microfluidically partitioned dual channels for accurate background subtraction in cellular binding studies by surface plasmon resonance microscopy

C Han, T Dong, P Wang, F Zhou - Analytical Chemistry, 2022 - ACS Publications
Unlike conventional surface plasmon resonance (SPR) using an antifouling film to anchor
biomolecules and a reference channel for background subtraction, SPR microscopy for …