[HTML][HTML] The scientific case for brain simulations

GT Einevoll, A Destexhe, M Diesmann, S Grün, V Jirsa… - Neuron, 2019 - cell.com
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

[HTML][HTML] Mechanisms of connectome development

M Kaiser - Trends in Cognitive Sciences, 2017 - cell.com
At the centenary of D'Arcy Thompson's seminal work 'On Growth and Form', pioneering the
description of principles of morphological changes during development and evolution …

Computing the local field potential (LFP) from integrate-and-fire network models

A Mazzoni, H Lindén, H Cuntz, A Lansner… - PLoS computational …, 2015 - journals.plos.org
Leaky integrate-and-fire (LIF) network models are commonly used to study how the spiking
dynamics of neural networks changes with stimuli, tasks or dynamic network states …

Multimodal modeling of neural network activity: computing LFP, ECoG, EEG, and MEG signals with LFPy 2.0

E Hagen, S Næss, TV Ness… - Frontiers in …, 2018 - frontiersin.org
Recordings of extracellular electrical, and later also magnetic, brain signals have been the
dominant technique for measuring brain activity for decades. The interpretation of such …

Uncovering circuit mechanisms of current sinks and sources with biophysical simulations of primary visual cortex

AE Rimehaug, AJ Stasik, E Hagen, YN Billeh… - elife, 2023 - elifesciences.org
Local field potential (LFP) recordings reflect the dynamics of the current source density
(CSD) in brain tissue. The synaptic, cellular, and circuit contributions to current sinks and …

Hybrid scheme for modeling local field potentials from point-neuron networks

E Hagen, D Dahmen, ML Stavrinou, H Lindén… - Cerebral …, 2016 - academic.oup.com
With rapidly advancing multi-electrode recording technology, the local field potential (LFP)
has again become a popular measure of neuronal activity in both research and clinical …

[KIRJA][B] Electric brain signals: foundations and applications of biophysical modeling

G Halnes, TV Ness, S Næss, E Hagen, KH Pettersen… - 2024 - books.google.com
It is common to study the electric activity of neurons by measuring the electric potential in the
extracellular space of the brain. However, interpreting such measurements requires …

Mechanisms underlying different onset patterns of focal seizures

Y Wang, AJ Trevelyan, A Valentin… - PLoS computational …, 2017 - journals.plos.org
Focal seizures are episodes of pathological brain activity that appear to arise from a
localised area of the brain. The onset patterns of focal seizure activity have been studied …

Computational modeling of single neuron extracellular electric potentials and network local field potentials using LFPsim

H Parasuram, B Nair, E D'Angelo, M Hines… - Frontiers in …, 2016 - frontiersin.org
Local Field Potentials (LFPs) are population signals generated by complex spatiotemporal
interaction of current sources and dipoles. Mathematical computations of LFPs allow the …

Active subthreshold dendritic conductances shape the local field potential

TV Ness, MWH Remme… - The Journal of physiology, 2016 - Wiley Online Library
Key points The local field potential (LFP), the low‐frequency part of extracellular potentials
recorded in neural tissue, is often used for probing neural circuit activity. Interpreting the LFP …