Hemorrhagic transformation in ischemic stroke and the role of inflammation

E Spronk, G Sykes, S Falcione, D Munsterman… - Frontiers in …, 2021 - frontiersin.org
Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

Prevalence of diabetes and its effects on stroke outcomes: a meta‐analysis and literature review

LH Lau, J Lew, K Borschmann, V Thijs… - Journal of diabetes …, 2019 - Wiley Online Library
Abstract Aims/Introduction Diabetes mellitus is an established risk factor for stroke and
maybe associated with poorer outcomes after stroke. The aims of the present literature …

Intensive vs standard treatment of hyperglycemia and functional outcome in patients with acute ischemic stroke: the SHINE randomized clinical trial

KC Johnston, A Bruno, Q Pauls, CE Hall, KM Barrett… - Jama, 2019 - jamanetwork.com
Importance Hyperglycemia during acute ischemic stroke is common and is associated with
worse outcomes. The efficacy of intensive treatment of hyperglycemia in this setting remains …

Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke: a statement for healthcare professionals from the …

BM Demaerschalk, DO Kleindorfer, OM Adeoye… - Stroke, 2016 - ahajournals.org
Purpose—To critically review and evaluate the science behind individual eligibility criteria
(indication/inclusion and contraindications/exclusion criteria) for intravenous recombinant …

Bioenergetic regulation of microglia

S Ghosh, E Castillo, ES Frias, RA Swanson - Glia, 2018 - Wiley Online Library
Microglia have diverse actions, ranging from synapse pruning in development to cytotoxic
effects in disease. Brain energy metabolism and substrate availability vary under normal and …

Diabetes, hyperglycaemia, and acute ischaemic stroke

MJA Luitse, GJ Biessels, GEHM Rutten… - The Lancet …, 2012 - thelancet.com
Diabetes and ischaemic stroke often arise together. People with diabetes have more than
double the risk of ischaemic stroke after correction for other risk factors, relative to …

Diabetes-related microvascular and macrovascular diseases in the physical therapy setting

WT Cade - Physical therapy, 2008 - academic.oup.com
Physical therapists commonly treat people with diabetes for a wide variety of diabetes-
associated impairments, including those from diabetes-related vascular disease. Diabetes is …

[HTML][HTML] Hyperglycemia: a prothrombotic factor?

BA Lemkes, J Hermanides, JH DeVries… - Journal of Thrombosis …, 2010 - Elsevier
Diabetes mellitus is characterized by a high risk of atherothrombotic events. What is more,
venous thrombosis has also been found to occur more frequently in this patient group. This …

Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management

ND Kruyt, GJ Biessels, JH DeVries… - Nature Reviews …, 2010 - nature.com
Patients with acute ischemic stroke frequently test positive for hyperglycemia, which is
associated with a poor clinical outcome. This association between poor glycemic control and …

Absolute and relative contraindications to IV rt-PA for acute ischemic stroke

JE Fugate, AA Rabinstein - The Neurohospitalist, 2015 - journals.sagepub.com
Most of the contraindications to the administration of intravenous (IV) recombinant tissue
plasminogen activator (rtPA) originated as exclusion criteria in major stroke trials. These …