Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection

L Pardo-López, M Soberón… - FEMS microbiology …, 2013 - academic.oup.com
Bacillus thuringiensis bacteria are insect pathogens that produce different Cry and Cyt toxins
to kill their hosts. Here we review the group of three-domain Cry (3d-Cry) toxins. Expression …

Bacillus thuringiensis: a story of a successful bioinsecticide

A Bravo, S Likitvivatanavong, SS Gill… - Insect biochemistry and …, 2011 - Elsevier
Bacillus thuringiensis (Bt) bacteria are insect pathogens that rely on insecticidal pore
forming proteins known as Cry and Cyt toxins to kill their insect larval hosts. At least four …

Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control

A Bravo, SS Gill, M Soberón - Toxicon, 2007 - Elsevier
Bacillus thuringiensis Crystal (Cry) and Cytolitic (Cyt) protein families are a diverse group of
proteins with activity against insects of different orders—Lepidoptera, Coleoptera, Diptera …

How do toxins from Bacillus thuringiensis kill insects? An evolutionary perspective

DG Heckel - Archives of insect biochemistry and physiology, 2020 - Wiley Online Library
Three‐domain Cry toxins from the bacterium Bacillus thuringiensis (Bt) are increasingly
used in agriculture to replace chemical insecticides in pest control. Most chemical …

Diversity of Bacillus thuringiensis crystal toxins and mechanism of action

MJ Adang, N Crickmore, JL Jurat-Fuentes - Advances in insect physiology, 2014 - Elsevier
Parasporal crystals produced by Bacillus thuringiensis (Bt) bacteria are the main virulence
factors underlying Bt toxicity to insects. Parasporal crystals are composed primarily of Cry …

Current models of the mode of action of Bacillus thuringiensis insecticidal crystal proteins: a critical review

V Vachon, R Laprade, JL Schwartz - Journal of invertebrate pathology, 2012 - Elsevier
Bacillus thuringiensis (Bt) Cry toxins constitute the active ingredient in the most widely used
biological insecticides and insect-resistant transgenic crops. A clear understanding of their …

Role of Receptors in Bacillus thuringiensis Crystal Toxin Activity

CR Pigott, DJ Ellar - Microbiology and molecular biology reviews, 2007 - journals.asm.org
Bacillus thuringiensis produces crystalline protein inclusions with insecticidal or nematocidal
properties. These crystal (Cry) proteins determine a particular strain's toxicity profile …

Bacillus thuringiensis: mechanism of action, resistance, and new applications: a review

ALA Melo, VT Soccol, CR Soccol - Critical reviews in …, 2016 - Taylor & Francis
Since the first report by Ishiwata in 1902 of a Bombyx mori infection, followed by the
description by Berliner, Bacillus thuringiensis (Bt) has become the main microorganism used …

Progress and prospects of CRISPR/Cas systems in insects and other arthropods

D Sun, Z Guo, Y Liu, Y Zhang - Frontiers in physiology, 2017 - frontiersin.org
Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-
associated gene Cas9 represent an invaluable system for the precise editing of genes in …

Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria

RA De Maagd, A Bravo, C Berry… - Annual review of …, 2003 - annualreviews.org
▪ Abstract Gram-positive spore-forming entomopathogenic bacteria can utilize a large variety
of protein toxins to help them invade, infect, and finally kill their hosts, through their action on …