Revolutionizing healthcare: the role of artificial intelligence in clinical practice
Introduction Healthcare systems are complex and challenging for all stakeholders, but
artificial intelligence (AI) has transformed various fields, including healthcare, with the …
artificial intelligence (AI) has transformed various fields, including healthcare, with the …
Precision medicine, AI, and the future of personalized health care
The convergence of artificial intelligence (AI) and precision medicine promises to
revolutionize health care. Precision medicine methods identify phenotypes of patients with …
revolutionize health care. Precision medicine methods identify phenotypes of patients with …
Multi-omics approaches to disease
High-throughput technologies have revolutionized medical research. The advent of
genoty** arrays enabled large-scale genome-wide association studies and methods for …
genoty** arrays enabled large-scale genome-wide association studies and methods for …
Pharmacogenomics in the clinic
After decades of discovery, inherited variations have been identified in approximately 20
genes that affect about 80 medications and are actionable in the clinic. And some …
genes that affect about 80 medications and are actionable in the clinic. And some …
Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium
CH van der Wouden… - Clinical …, 2017 - Wiley Online Library
Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …
into routine care remains limited. Opportunely, several implementation studies and …
Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine
ABSTRACT Introduction: Proton Pump inhibitors (PPIs) are commonly used for a variety of
acid related disorders. Despite the overall effectiveness and safety profile of PPIs, some …
acid related disorders. Despite the overall effectiveness and safety profile of PPIs, some …
Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good
The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers
Although the field of pharmacogenetics has existed for decades, practioners have been slow
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …
Implementing genomic medicine in the clinic: the future is here
TA Manolio, RL Chisholm, B Ozenberger… - Genetics in …, 2013 - nature.com
Although the potential for genomics to contribute to clinical care has long been anticipated,
the pace of defining the risks and benefits of incorporating genomic findings into medical …
the pace of defining the risks and benefits of incorporating genomic findings into medical …
Clinical decision support: a 25 year retrospective and a 25 year vision
Objective: The objective of this review is to summarize the state of the art of clinical decision
support (CDS) circa 1990, review progress in the 25 year interval from that time, and provide …
support (CDS) circa 1990, review progress in the 25 year interval from that time, and provide …