Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

A systematic literature review was undertaken to determine if conditioned pain modulation
(CPM) is reliable. Longitudinal, English language observational studies of the repeatability …

There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …

Protocols for testing conditioned pain modulation (CPM) vary between different labs/clinics.
In order to promote research and clinical application of this tool, we summarize the …

Exercise and physical activity is recommended treatment for a wide range of chronic pain
conditions. In addition to several well-documented effects on physical and mental health, 8 …

Abstract Development and application of psychophysical test paradigms to assess
endogenous pain modulation in healthy controls and in patients yielded large body of data …

Conditioned pain modulation (CPM) is a centrally processed measure of the net effect of the
descending pain pathway. This comprises both the facilitatory as well as the inhibitory effect …

To study the characteristics of temporal summation (TS) and conditioned pain modulation
(CPM) in fibromyalgia (FM) patients, we systematically searched Pubmed and EMBASE for …

The reviewed literature refines the methodology used for eliciting CPM responses and
characterizing their physiological attributes in healthy individuals and pain patients, and …

This study aims to individualize the selection of drugs for neuropathic pain by examining the
potential coupling of a given drug's mechanism of action with the patient's pain modulation …