Irisin in metabolic diseases

SA Polyzos, AD Anastasilakis, ZA Efstathiadou… - Endocrine, 2018 - Springer
Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …

Non-alcoholic fatty liver disease in women with polycystic ovary syndrome: systematic review and meta-analysis

ALL Rocha, LC Faria, TCM Guimarães… - Journal of …, 2017 - Springer
Purpose Non-alcoholic fatty liver disease (NAFLD) is an insidious pathologic condition that
can manifest from simple steatosis to steatohepatitis (NASH) with potential progression to …

Mechanisms in endocrinology: the sexually dimorphic role of androgens in human metabolic disease

L Schiffer, P Kempegowda, W Arlt… - European journal of …, 2017 - academic.oup.com
Female androgen excess and male androgen deficiency manifest with an overlap**
adverse metabolic phenotype, including abdominal obesity, insulin resistance, type 2 …

A potential link between polycystic ovary syndrome and non-alcoholic fatty liver disease: an update meta-analysis

J Wu, XY Yao, RX Shi, SF Liu, XY Wang - Reproductive Health, 2018 - Springer
Background Epidemiological literature regarding the effect of polycystic ovary syndrome
(PCOS) as a risk factor for non-alcoholic fatty liver disease (NAFLD) remains inconsistent …

Nonalcoholic fatty liver disease in women and girls with polycystic ovary syndrome

C Falzarano, T Lofton, A Osei-Ntansah… - The Journal of …, 2022 - academic.oup.com
Context Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of liver damage due
to excessive hepatic lipid accumulation. Recent research has demonstrated a high …

Nonalcoholic fatty liver disease in women with polycystic ovary syndrome

SA Paschou, SA Polyzos, P Anagnostis, DG Goulis… - Endocrine, 2020 - Springer
Polycystic ovary syndrome (PCOS) affects 6–15% of women of reproductive age.
Nonalcoholic fatty liver disease (NAFLD) affects 25–30% of the general population and its …

Menopause and non-alcoholic fatty liver disease: a review focusing on therapeutic perspectives

V Venetsanaki, SA Polyzos - Current Vascular Pharmacology, 2019 - ingentaconnect.com
There is increasing evidence that menopause is associated with the progression and
severity of non-alcoholic fatty liver disease (NAFLD). Estrogen deficiency worsens non …

Insulin resistance and hyperandrogenism drive steatosis and fibrosis risk in young females with PCOS

S Petta, A Ciresi, J Bianco, V Geraci, R Boemi… - PloS one, 2017 - journals.plos.org
Background and aims Nonalcoholic fatty liver disease (NAFLD) and polycystic ovary
syndrome (PCOS) recognize obesity and insulin resistance (IR) as common pathogenic …

Non-alcoholic fatty liver disease across endocrinopathies: Interaction with sex hormones

S Arefhosseini, M Ebrahimi-Mameghani… - Frontiers in …, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most frequent chronic liver
disease globally. NAFLD is strongly associated with metabolic syndrome and it has been …

Non-alcoholic fatty liver disease through the female lifespan: the role of sex hormones

K Pafili, SA Paschou, E Armeni, SA Polyzos… - Journal of …, 2022 - Springer
The prevalence of non-alcoholic fatty liver disease (NAFLD) differs between various stages
of the female lifespan. The aim of this review is to summarize current evidence on the …