[HTML][HTML] The risk of disease progression in peripheral arterial disease is higher than expected: a meta-analysis of mortality and disease progression in peripheral …

B Sigvant, F Lundin, E Wahlberg - European Journal of Vascular and …, 2016 - Elsevier
Objective Peripheral arterial disease (PAD) afflicts up to 20% of older people and is
associated with a high risk of cardiovascular (CV) morbidity, but a rather low risk of …

Critical limb ischemia: current challenges and future prospects

L Uccioli, M Meloni, V Izzo, L Giurato… - Vascular health and …, 2018 - Taylor & Francis
Critical limb ischemia (CLI) is considered the most severe pattern of peripheral artery
disease. It is defined by the presence of chronic ischemic rest pain, ulceration or gangrene …

[HTML][HTML] Global vascular guidelines on the management of chronic limb-threatening ischemia

MS Conte, AW Bradbury, P Kolh, JV White… - European Journal of …, 2019 - Elsevier
Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

[HTML][HTML] The society for vascular surgery lower extremity threatened limb classification system: risk stratification based on wound, ischemia, and foot infection (WIfI)

JL Mills Sr, MS Conte, DG Armstrong… - Journal of vascular …, 2014 - Elsevier
Critical limb ischemia, first defined in 1982, was intended to delineate a subgroup of patients
with a threatened lower extremity primarily because of chronic ischemia. It was the intent of …

Association of statin dose with amputation and survival in patients with peripheral artery disease

S Arya, A Khakharia, ZO Binney, RR DeMartino… - Circulation, 2018 - Am Heart Assoc
Background: Statin dose guidelines for patients with peripheral artery disease (PAD) are
largely based on coronary artery disease and stroke data. The aim of this study is to …

Critical limb ischemia: current trends and future directions

M Teraa, MS Conte, FL Moll… - Journal of the American …, 2016 - Am Heart Assoc
Critical limb ischemia (CLI), which is at the end of the peripheral artery disease (PAD)
spectrum, is associated with excessively high risk for cardiovascular events, including …

[HTML][HTML] Critical limb ischemia

VN Varu, ME Hogg, MR Kibbe - Journal of vascular surgery, 2010 - Elsevier
Critical limb ischemia (CLI) continues to be a significantly morbid disease process for the
aging population. Rigid guidelines for the management of patients with CLI are …

Global and regional burden of death and disability from peripheral artery disease: 21 world regions, 1990 to 2010

UKA Sampson, FGR Fowkes, MM McDermott… - Global heart, 2014 - Elsevier
A comprehensive and systematic assessment of disability and mortality due to lower
extremity peripheral artery disease (PAD) is lacking. Therefore, we estimated PAD deaths …

Atherosclerotic risk and statin use among patients with peripheral artery disease

LD Colantonio, D Hubbard, KL Monda, KE Mues… - Journal of the American …, 2020 - jacc.org
Background Peripheral artery disease (PAD) is associated with increased risk for
atherosclerotic cardiovascular disease (ASCVD) events. Objectives The goal of this study …

Mendelian randomization analyses reveal causal relationships between the human microbiome and longevity

X Liu, L Zou, C Nie, Y Qin, X Tong, J Wang, H Yang… - Scientific reports, 2023 - nature.com
Although recent studies have revealed the association between the human microbiome
especially gut microbiota and longevity, their causality remains unclear. Here, we assess the …