Alkaloids from plants with antimalarial activity: a review of recent studies

PF Uzor - Evidence‐Based Complementary and Alternative …, 2020 - Wiley Online Library
Malaria is one of the major health problems in develo** countries. The disease kills a
large number of people every year and also affects financial status of many countries …

Medicinal plants: a source of anti-parasitic secondary metabolites

M Wink - Molecules, 2012 - mdpi.com
This review summarizes human infections caused by endoparasites, including protozoa,
nematodes, trematodes, and cestodes, which affect more than 30% of the human …

Antimicrobial plant metabolites: structural diversity and mechanism of action

NS Radulovic, PD Blagojevic… - Current medicinal …, 2013 - ingentaconnect.com
Microbial infectious diseases continue to be one of the leading causes of morbidity and
mortality. It has been estimated that microbial species comprise about 60% of the Earth's …

Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya

DO Ochwang'i, CN Kimwele, JA Oduma… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Traditional medicine plays a critical role in treatment of
chronic debilitating and life threatening conditions and diseases. Cancer is one such …

Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids

P Amoa Onguéné, F Ntie-Kang, LL Lifongo, JC Ndom… - Malaria journal, 2013 - Springer
Traditional medicine caters for about 80% of the health care needs of many rural
populations around the world, especially in develo** countries. In addition, plant-derived …

Quinoline-based antimalarial hybrid compounds

S Vandekerckhove, M D'hooghe - Bioorganic & medicinal chemistry, 2015 - Elsevier
Quinoline-containing compounds, such as quinine and chloroquine, have a long-standing
history as potent antimalarial agents. However, the increasing resistance of the Plasmodium …

The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids

F Ntie-Kang, PA Onguéné, LL Lifongo, JC Ndom… - Malaria journal, 2014 - Springer
Malaria is currently a public health concern in many countries in the world due to various
factors which are not yet under check. Drug discovery projects targeting malaria often resort …

A call for using natural compounds in the development of new antimalarial treatments–an introduction

H Ginsburg, E Deharo - Malaria journal, 2011 - Springer
Natural compounds, mostly from plants, have been the mainstay of traditional medicine for
thousands of years. They have also been the source of lead compounds for modern …

Natural products as starting points for future anti-malarial therapies: going back to our roots?

TNC Wells - Malaria journal, 2011 - Springer
Background The discovery and development of new anti-malarials are at a crossroads.
Fixed dose artemisinin combination therapy is now being used to treat a hundred million …