Diabetic peripheral neuropathy (DPN) is a chronic and prevalent metabolic disease that
gravely endangers human health and seriously affects the quality of life of hyperglycemic …

Rheumatic diseases, such as osteoarthritis and rheumatoid arthritis, affect over 750 million
people worldwide and contribute to approximately 40% of chronic pain cases. Inflammation …

Although largely confined to the airways, SARS-CoV-2 infection has been associated with
sensory abnormalities that manifest in both acute and chronic phenotypes. To gain insight …

Abstract Background Even though numerous Histone deacetylase inhibitors (HDACi) have
been approved for the treatment of different types of cancer, and others are in clinical trials …

Background Neuropathic pain remains a formidable challenge for modern medicine. The
first‐line pharmacological therapies exhibit limited efficacy and unfavorable side effect …

Migraine is the sixth most prevalent disease worldwide but the mechanisms that underlie
migraine chronicity are poorly understood. Cytoskeletal flexibility is fundamental to neuronal …

Rheumatic diseases, such as osteoarthritis and rheumatoid arthritis, affect over 750 million
people worldwide and contribute to approximately 40% of chronic pain cases. Inflammation …

Peripheral neuropathy, which is the result of nerve damage from lesions or disease,
continues to be a major health concern due to the common manifestation of neuropathic …

Chemotherapy-induced peripheral neuropathy (CIPN) impacts a growing number of cancer
survivors and treatment options are limited. Histone deacetylase 6 (HDAC6) inhibitors are …

Tricyclic antidepressants (TCAs), such as desipramine (DMI), are effective at managing
neuropathic pain symptoms but often take several weeks to become effective and also lead …