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Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities
N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
The role of the microbiome in the neurobiology of social behaviour
A Sarkar, S Harty, KVA Johnson, AH Moeller… - Biological …, 2020 - Wiley Online Library
Microbes colonise all multicellular life, and the gut microbiome has been shown to influence
a range of host physiological and behavioural phenotypes. One of the most intriguing and …
a range of host physiological and behavioural phenotypes. One of the most intriguing and …
A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism
The social impairments of autism spectrum disorder (ASD) have a major impact on quality of
life, yet there are no medications that effectively treat these core social behavior deficits …
life, yet there are no medications that effectively treat these core social behavior deficits …
Meta-analysis: pharmacologic treatment of restricted and repetitive behaviors in autism spectrum disorders
MS Zhou, M Nasir, LC Farhat, M Kook… - Journal of the American …, 2021 - Elsevier
Objective To examine the efficacy of pharmacological treatments for restricted and repetitive
behaviors (RRB) in autism spectrum disorders (ASD). Method We searched PubMed …
behaviors (RRB) in autism spectrum disorders (ASD). Method We searched PubMed …
Modulation of social behavior by distinct vasopressin sources
N Rigney, GJ de Vries, A Petrulis - Frontiers in Endocrinology, 2023 - frontiersin.org
The neuropeptide arginine-vasopressin (AVP) is well known for its peripheral effects on
blood pressure and antidiuresis. However, AVP also modulates various social and anxiety …
blood pressure and antidiuresis. However, AVP also modulates various social and anxiety …
Complementary neural circuits for divergent effects of oxytocin: social approach versus social anxiety
MQ Steinman, N Duque-Wilckens, BC Trainor - Biological psychiatry, 2019 - Elsevier
Oxytocin (OT) is widely known for promoting social interactions, but there is growing
appreciation that it can sometimes induce avoidance of social contexts. The social salience …
appreciation that it can sometimes induce avoidance of social contexts. The social salience …
Nebulized vasopressin penetrates CSF and improves social cognition without inducing aggression in a rhesus monkey model of autism
Low cerebrospinal (CSF) arginine vasopressin (AVP) concentration is a biomarker of social
impairment in low-social monkeys and children with autism, suggesting that AVP …
impairment in low-social monkeys and children with autism, suggesting that AVP …
Neonatal CSF vasopressin concentration predicts later medical record diagnoses of autism spectrum disorder
O Oztan, JP Garner, JN Constantino… - Proceedings of the …, 2020 - pnas.org
Autism spectrum disorder (ASD) is a brain disorder characterized by social impairments.
ASD is currently diagnosed on the basis of behavioral criteria because no robust biomarkers …
ASD is currently diagnosed on the basis of behavioral criteria because no robust biomarkers …
Fluid and imaging biomarkers for Huntington's disease
P Zeun, RI Scahill, SJ Tabrizi, EJ Wild - Molecular and Cellular …, 2019 - Elsevier
Huntington's disease is a chronic progressive neurodegenerative condition for which there
is no disease-modifying treatment. The known genetic cause of Huntington's disease makes …
is no disease-modifying treatment. The known genetic cause of Huntington's disease makes …
Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability
RJ Wang, GWC Thomas, M Raveendran… - Genome …, 2020 - genome.cshlp.org
Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic
disorders. Mutational burden has been linked to complex disease, including …
disorders. Mutational burden has been linked to complex disease, including …