Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …

Coronary artery disease (CAD) is an important contributor to the cardiovascular burden in
cancer survivors. This review identifies features that could help guide decisions about the …

Opinion statement Cardiotoxicity has emerged as a serious outcome catalyzed by various
therapeutic targets in the field of cancer treatment, which includes chemotherapy, radiation …

Cellular senescence is characteristic of the development and progression of multiple age-
associated diseases. Accumulation of senescent cells in the heart contributes to various age …

The evolution of cancer treatment and development of new classes of anticancer therapies
have continued to revolutionize the field of oncology. New therapies including targeted …

Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …

Drug-induced cardiotoxicity is a primary concern in both drug development and clinical
practice. Although the heart is not a common target for adverse drug reactions, some drugs …

Excessive macroautophagy/autophagy is one of the causes of cardiomyocyte death induced
by cardiovascular diseases or cancer therapy, yet the underlying mechanism remains …

Cardiovascular diseases are the most common cause of death globally. Accurately
modeling cardiac homeostasis, dysfunction, and drug response lies at the heart of cardiac …

Simple Summary In recent years, there have been several advances in the care of advanced
bladder cancer, highlighted by the addition of immune checkpoint inhibitors to the care of …