Humanized anti-TGF-beta antibodies

CW Adams, N Ferrara, EH Filvaroff, W Mao… - US Patent …, 2009 - Google Patents
2005-08-23 Assigned to GENENTECH, INC. reassignment GENENTECH, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Binding polypeptides with diversified and consensus VH/VL hypervariable sequences

MS Dennis, WC Liang, Y Wu - US Patent 8,679,490, 2014 - Google Patents
HXCHCVDVKSCDHU-LULTVBGHSA-N Calicheamicin Chemical compound C1 [C@
H](OC)[C@@ H](NCC) CO [C@ H] 1O [C@ H] 1 [C@ H](O [C@@ H] 2C\3= C (NC (= O) OC) …

Bacterial host strains for producing proteolytically sensitive polypeptides

G Georgiou, F Baneyx - US Patent 5,508,192, 1996 - Google Patents
The invention relates to methods of producing recombinant polypeptides in protease-de?
cient bacterial hosts. Con structs of single, double, triple and quadruple protease de? cient …

Bispecific antibodies comprising a disulfide stabilized-Fv fragment

U Brinkmann, A Haas, S Metz, JM Schanzer - US Patent 9,879,095, 2018 - Google Patents
US9879095B2 - Bispecific antibodies comprising a disulfide stabilized-Fv fragment - Google
Patents US9879095B2 - Bispecific antibodies comprising a disulfide stabilized-Fv fragment …

Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes

LC Simmons, L Klimowski, D Reilly… - US Patent …, 2005 - Google Patents
27 1) negative Control 2) TIR 1-light, TIR 1-heavy, polycistronic 3) TIR 3-light, TIR 1-heavy,
polycistronic 4) TIR 1-light, TIR 3-heavy, polycistronic 5) TIR 1-light, TR 1-heavy, separate …

Methods and compositions for increasing antibody production

D Reilly, D Yansura - US Patent 7,608,429, 2009 - Google Patents
US7608429B2 - Methods and compositions for increasing antibody production - Google Patents
US7608429B2 - Methods and compositions for increasing antibody production - Google Patents …

Multispecific antibodies comprising full length antibodies and single chain fab fragments

U Brinkmann, P Bruenker, R Croasdale, C Klein… - US Patent …, 2016 - Google Patents
US9382323B2 - Multispecific antibodies comprising full length antibodies and single chain fab
fragments - Google Patents US9382323B2 - Multispecific antibodies comprising full length …

Antibodies with altered effector functions

L Krummen, D Reilly, S Weikert - US Patent App. 10/934,087, 2005 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …

Heteromultimeric molecules

A Huang, B Moffat, D Yansura - US Patent App. 11/218,286, 2006 - Google Patents
US20060204493A1 - Heteromultimeric molecules - Google Patents US20060204493A1 -
Heteromultimeric molecules - Google Patents Heteromultimeric molecules Download PDF …

Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture

L Simmons - US Patent 7,575,893, 2009 - Google Patents
US7575893B2 - Methods for producing humanized antibodies and improving yield of
antibodies or antigen binding fragments in cell culture - Google Patents US7575893B2 …