Inhibitory immune checkpoint receptors and ligands as prognostic biomarkers in COVID-19 patients

MA Al-Mterin, A Alsalman, E Elkord - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. During T-cell activation,
the immune system uses different checkpoint pathways to maintain co-inhibitory and co …

Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients

E Cervantes-Alvarez, NL la Rosa, MS la Mora… - Scientific Reports, 2022 - nature.com
Severe COVID-19 is associated with a systemic hyperinflammatory response leading to
acute respiratory distress syndrome (ARDS), multi-organ failure, and death. Galectin-3 is a ß …

[HTML][HTML] In silico analysis of the multi-targeted mode of action of ivermectin and related compounds

M Aminpour, M Cannariato, J Preto, ME Safaeeardebili… - Computation, 2022 - mdpi.com
Some clinical studies have indicated activity of ivermectin, a macrocyclic lactone, against
COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not …

Novel inflammatory biomarkers in the prognosis of COVID-19

K Zhan, L Wang, H Lin, X Fang… - … in Respiratory Disease, 2023 - journals.sagepub.com
Background: The central role of inflammatory progression in the development of
Coronavirus disease 2019 (COVID-19), especially in severe cases, is indisputable …

Examining sialic acid derivatives as potential inhibitors of SARS-CoV-2 spike protein receptor binding domain

T Banerjee, A Gosai, N Yousefi… - Journal of …, 2024 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has been the primary
reason behind the COVID-19 global pandemic which has affected millions of lives …

Bovine milk glycoproteins inhibit SARS-CoV-2 and influenza virus co-infection

H Yu, W Chen, J Shu, X Wu, J Quan, H Cheng, X Bao… - bioRxiv, 2023 - biorxiv.org
The attachment of S1 subunit of spike (S) protein to angiotensin-converting enzyme 2
(ACE2) is the first and crucial step of SARS-CoV-2 infection. Although S protein and ACE2 …

[PDF][PDF] In Silico Analysis of the Multi-Targeted Mode of Action of Ivermectin and Related Compounds. Computation 2022, 10, 51

M Aminpour, M Cannariato, J Preto, ME Safaeeardebili… - 2022 - researchgate.net
Some clinical studies have indicated activity of ivermectin, a macrocyclic lactone, against
COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not …

Analysis of CD147 inhibitors such as ivermectin, azithromycin with respect to their potential therapeutic use against the emerging COVID mutations

E Safaeeardebili - 2022 - webthesis.biblio.polito.it
There has been reported by clinical scientists that a macrocyclic lactone such as ivermectin
showed some activity against new emerging SARS CoV-2 (COVID-19). Since a biological …