The past 20 years have seen dramatic changes in the delivery of radiation therapy, but the
impact of radiobiology on the clinic has been far less substantial. A major consideration in …

In humans, selenium was hypothesized to lower the risk of several chronic diseases, mainly
due to the antioxidant activity of selenium-containing proteins. Recent epidemiologic and …

With the advancement of radiological medicine and nuclear industry technology, radiation is
increasingly used to diagnose human health disorders. However, large-scale nuclear …

Selenoprotein P (SELENOP) is an emerging marker of the nutritional status of selenium and
of various diseases, however, its chemical characteristics still need to be investigated and …

Pharmacologic ascorbate treatment (P-AscH−, high-dose, intravenous vitamin C) results in a
transient short-term increase in the flux of hydrogen peroxide that is preferentially cytotoxic …

Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells
and increases in toxicity when used in combination with radiation. In addition to various …

Radiotherapy (RT) is among the most prevalent approaches to cancer treatment, yet it also
causes severe side effects in patients that limit its efficacy and application. In recent …

Radiation-induced heart disease (RIHD), characterized by severe oxidative stress and
immune dysregulation, is a serious condition affecting cancer patients undergoing thoracic …

The aim of the present study was to examine the role of Selenoprotein W (Sepw1) in
modulating the expression of other selenoproteins. In the present study, we silenced and …

Selenomethionine (SeMet) is a widely used food supplement. However, the research on the
effect of SeMet on intestinal immune function is not enough. Therefore, in this experiment …