The Arg–Phe‐amide peptide 26RFa/glutamine RF‐amide peptide and its receptor: IUPHAR Review 24
J Leprince, D Bagnol, R Bureau… - British journal of …, 2017 - Wiley Online Library
The RFamide neuropeptide 26RFa was first isolated from the brain of the European green
frog on the basis of cross‐reactivity with antibodies raised against bovine neuropeptide FF …
frog on the basis of cross‐reactivity with antibodies raised against bovine neuropeptide FF …
The neuropeptide 26RFa (QRFP) and its role in the regulation of energy homeostasis: a mini-review
N Chartrel, M Picot, M El Medhi, A Arabo… - Frontiers in …, 2016 - frontiersin.org
This mini-review deals with the neuropeptide 26RFa (or QRFP) which is a member of the
RFamide peptide family discovered simultaneously by three groups in 2003. 26RFa (or its N …
RFamide peptide family discovered simultaneously by three groups in 2003. 26RFa (or its N …
Beneficial effects of combination therapy of phloretin and metformin in streptozotocin-induced diabetic rats and improved insulin sensitivity in vitro
X Shen, L Wang, N Zhou, S Gai, X Liu, S Zhang - Food & function, 2020 - pubs.rsc.org
The GLUT4 and PI3K/AKT signaling pathways are the key sensors of energy status and they
regulate glucose and lipid metabolism. Phloretin activates the PI3K/AKT pathway by …
regulate glucose and lipid metabolism. Phloretin activates the PI3K/AKT pathway by …
Phloretin exerts hypoglycemic effect in streptozotocin-induced diabetic rats and improves insulin resistance in vitro
X Shen, N Zhou, L Mi, Z Hu, L Wang, X Liu… - Drug Design …, 2017 - Taylor & Francis
The present study investigated the possible antiobesity and hypoglycemic effects of
phloretin (Ph). In an attempt to discover the hypoglycemic effect and potential mechanism of …
phloretin (Ph). In an attempt to discover the hypoglycemic effect and potential mechanism of …
QRFP-deficient mice are hypophagic, lean, hypoactive and exhibit increased anxiety-like behavior
How the hypothalamus transmits hunger information to other brain regions to govern whole
brain function to orchestrate feeding behavior has remained largely unknown. Our present …
brain function to orchestrate feeding behavior has remained largely unknown. Our present …
Maternal nutrient restriction disrupts gene expression and metabolites associated with urea cycle, steroid synthesis, glucose homeostasis, and glucuronidation in fetal …
S Muroya, Y Zhang, K Otomaru, K Oshima, I Oshima… - Metabolites, 2022 - mdpi.com
This study aimed to understand the mechanisms underlying the effects of maternal
undernutrition (MUN) on liver growth and metabolism in Japanese Black fetal calves (8.5 …
undernutrition (MUN) on liver growth and metabolism in Japanese Black fetal calves (8.5 …
The 26RFa (QRFP)/GPR103 neuropeptidergic system: A key regulator of energy and glucose metabolism
M Devère, S Takhlidjt, G Prévost, N Chartrel… - …, 2024 - karger.com
Background: Obesity and type 2 diabetes are strongly associated pathologies, currently
considered as a worldwide epidemic problem. Understanding the mechanisms that drive the …
considered as a worldwide epidemic problem. Understanding the mechanisms that drive the …
Regulation of the expression of corticotropin-releasing factor gene by pyroglutamylated RFamide peptide in rat hypothalamic 4B cells
N Ishigame, K Kageyama, S Takayasu, K Furumai… - Endocrine …, 2016 - jstage.jst.go.jp
Pyroglutamylated RFamide peptide (QRFP), an important regulator of metabolism and
energy homeostasis, has orexigenic effects. QRFP acts via a specific receptor, Gpr103 …
energy homeostasis, has orexigenic effects. QRFP acts via a specific receptor, Gpr103 …
Ontogeny of QRFP and its receptor expression in mouse testis during post-natal development
Pyroglutamylated RFamide peptide (QRFP), a neuropeptide, binds to its receptor GPR103
and influences various biological functions. In the present study, expression and localization …
and influences various biological functions. In the present study, expression and localization …
[HTML][HTML] Two naturally occurring mutations of human GPR103 define distinct G protein selection bias
Q Ma, Z Cao, H Li, W Wang, Y Tian, L Yan… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The neuropeptide 26RFa plays important roles in the regulation of many physiological
functions. 26RFa has been recognized as an endogenous ligand for receptor GPR103. In …
functions. 26RFa has been recognized as an endogenous ligand for receptor GPR103. In …