A scalable ISFET sensing and memory array with sensor auto-calibration for on-chip real-time DNA detection

N Moser, J Rodriguez-Manzano… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a novel CMOS-based system-onchip with a 78× 56 ion-sensitive field-
effect transistor array using in-pixel quantization and compensation of sensor nonidealities …

Improving dengue diagnostics and management through innovative technology

J Rodriguez-Manzano, PY Chia, TW Yeo… - Current infectious …, 2018 - Springer
Abstract Purpose of Review Dengue continues to be a major global public health threat.
Symptomatic infections can cause a spectrum of disease ranging from a mild febrile illness …

Complementary metal–oxide–semiconductor potentiometric field-effect transistor array platform using sensor learning for multi-ion imaging

N Moser, CL Leong, Y Hu, C Cicatiello… - Analytical …, 2020 - ACS Publications
This work describes an array of 1024 ion-sensitive field-effect transistors (ISFETs) using
sensor-learning techniques to perform multi-ion imaging for concurrent detection of …

A 12.8 k current-mode velocity-saturation ISFET array for on-chip real-time DNA detection

N Miscourides, LS Yu… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a large-scale CMOS chemicalsensing array operating in current mode
for real-time ion imaging and detection of DNA amplification. We show that the currentmode …

Sensitive detection of asymptomatic and symptomatic malaria with seven novel parasite-specific LAMP assays and translation for use at point-of-care

K Malpartida-Cardenas, N Moser, F Ansah… - Microbiology …, 2023 - journals.asm.org
Human malaria is a life-threatening parasitic disease with high impact in the sub-Saharan
Africa region, where 95% of global cases occurred in 2021. While most malaria diagnostic …

A dual-sensing thermo-chemical ISFET array for DNA-based diagnostics

M Cacho-Soblechero… - … Circuits and Systems, 2020 - ieeexplore.ieee.org
This paper presents a 32× 32 ISFET array with inpixel dual-sensing and programmability
targeted for on-chip DNA amplification detection. The pixel architecture provides thermal …

Mechanisms for enhancement of sensing performance in CMOS ISFET arrays using reactive ion etching

N Moser, C Panteli, K Fobelets, P Georgiou - Sensors and Actuators B …, 2019 - Elsevier
In this work, we investigate the impact of successively removing the passivation layers of
ISFET sensors implemented in a standard CMOS process to improve sensing performance …

[HTML][HTML] Rapid and sensitive detection of azole-resistant Aspergillus fumigatus by tandem repeat loop-mediated isothermal amplification

LS Yu, J Rodriguez-Manzano… - The Journal of Molecular …, 2019 - Elsevier
Invasive fungal infections caused by multiazole-resistant Aspergillus fumigatus are
associated with increasing rates of mortality in susceptible patients. Current methods of …

Simultaneous single-channel multiplexing and quantification of carbapenem-resistant genes using multidimensional standard curves

J Rodriguez-Manzano, A Moniri… - Analytical …, 2019 - ACS Publications
Multiplexing and quantification of nucleic acids, both have, in their own right, significant and
extensive use in biomedical related fields. Currently, the ability to detect several nucleic acid …

A trapped charge compensation scheme for ISFET based translinear circuits

M Gantier, M Kalofonou… - 2018 IEEE International …, 2018 - ieeexplore.ieee.org
A trapped charge compensation scheme for ISFET based translinear circuits is presented,
as part of a system for prediction of cancer risk, based on DNA methylation. Each pixel is …