The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

The frontal lobes are important for cognitive control, yet their functional organization remains
controversial. An influential class of theory proposes that the frontal lobes are organized …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

Dorsal anterior cingulate cortex (dACC) carries a wealth of value-related information
necessary for regulating behavioral flexibility and persistence. It signals error and reward …

The dorsal anterior cingulate cortex (dACC) has attracted great interest from neuroscientists
because it is associated with so many important cognitive functions. Despite, or perhaps …

Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …

Understanding how the brain computes value is a basic question in neuroscience. Although
individual studies have driven this progress, meta-analyses provide an opportunity to test …

Successful goal-directed behavior requires not only correct action selection, planning, and
execution but also the ability to flexibly adapt behavior when performance problems occur or …

There is accumulating neural evidence to support the existence of two distinct systems for
guiding action selection, a deliberative" model-based" and a reflexive" model-free" system …

The frontal lobes subserve decision-making and executive control—that is, the selection and
coordination of goal-directed behaviors. Current models of frontal executive function …