Accumulating evidence supports a complex relationship between adiposity and
osteoporosis in overweight/obese individuals, with local interactions and endocrine …

Evidence presented over the past 20years have has shown that long-chain polyunsaturated
fatty acids (LCPUFAs), especially the n-3 fatty acids such as eicospentaenoic acid (EPA) …

Food enrichment with nutraceuticals is an important goal, but its effectiveness in preventing
diseases depends on preserving the functionality and bioavailability of the bioactive …

Osteoporosis and obesity remain a major public health concern through its associated
fragility and fractures. Several animal models for the study of osteoporotic bone loss, such as …

Obesity adversely affects bone and fat metabolism in mice and humans. Omega-3
polyunsaturated fatty acids (omega-3 PUFAs) have been shown to improve glucose …

Fish oil rich in n− 3 polyunsaturated fatty acids, especially eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) protects inflammation induced bone loss in chronic …

NF‐κB is a transcriptional activator of many genes, including some that lead to muscle
atrophy and bone resorption—significant concerns for astronauts. NF‐κB activation is …

Aging is a complex biological process driven by a selective class of molecules and
pathways that affect overall deterioration of physiological functions to increase the risk of …

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs, n-3 PUFAs), including eicosapentaenoic
acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic acid (ALA), are essential …

Breast cancer patients often develop bone metastasis evidenced by osteolytic lesions,
leading to severe pain and bone fracture. Attenuation of breast cancer metastasis to bone …