Cancer multidrug-resistance reversal by ABCB1 inhibition: A recent update

K Engle, G Kumar - European journal of medicinal chemistry, 2022 - Elsevier
Chemotherapy is one of the most common treatments for cancer that uses one or more anti-
cancer drugs as a part of the standardized chemotherapy regimen. Cytotoxic chemicals …

Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box

P Martins, J Jesus, S Santos, LR Raposo… - Molecules, 2015 - mdpi.com
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …

Synthesis and therapeutic potential of imidazole containing compounds

A Siwach, PK Verma - BMC chemistry, 2021 - Springer
Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen,
four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole. It contains two …

Understanding functional group effect on corrosion inhibition efficiency of selected organic compounds

H Assad, A Kumar - Journal of Molecular Liquids, 2021 - Elsevier
Organic compounds exhibit notable efficiency towards inhibition of corrosion on numerous
metals and alloys. Because of its vast uses in counteracting material deterioration, the use of …

Imidazole: synthesis, functionalization and physicochemical properties of a privileged structure in medicinal chemistry

HV Tolomeu, CAM Fraga - Molecules, 2023 - mdpi.com
Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …

Substituents effect on corrosion inhibition performance of organic compounds in aggressive ionic solutions: a review

C Verma, LO Olasunkanmi, EE Ebenso… - Journal of Molecular …, 2018 - Elsevier
One of the factors that limit the use of synthetic organic compounds as corrosion inhibitors is
the series of trials associated with traditional syntheses that have to be carried out in the …

Imidazoles as potential anticancer agents

I Ali, MN Lone, HY Aboul-Enein - MedChemComm, 2017 - pubs.rsc.org
Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …

Visible light photocatalysis in the synthesis of pharmaceutically relevant heterocyclic scaffolds

V Srivastava, PK Singh, S Tivari… - Organic Chemistry …, 2022 - pubs.rsc.org
Visible light and photoredox catalysis have emerged as a powerful and long-lasting tool for
organic synthesis, demonstrating the importance of a variety of chemical bond formation …

[HTML][HTML] Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

IV Machado, JRN Dos Santos, MAP Januario… - Ultrasonics …, 2021 - Elsevier
Ultrasound is an essential technique to improve organic synthesis from the point of view of
green chemistry, as it can promote better yields and selectivities, in addition to shorter …

Preparation of imidazole acids grafted chitosan with enhanced antioxidant, antibacterial and antitumor activities

B Ma, J Zhang, Y Mi, Q Miao, W Tan, Z Guo - Carbohydrate Polymers, 2023 - Elsevier
Herein, imidazole acids grafted chitosan derivatives were synthesized, including HACC,
HACC derivatives, TMC, TMC derivatives, amidated chitosan and amidated chitosan …