Epidemiology of prostate cancer

P Rawla - World journal of oncology, 2019 - pmc.ncbi.nlm.nih.gov
Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Advances and development of prostate cancer, treatment, and strategies: A systemic review

S Belkahla, I Nahvi, S Biswas, I Nahvi… - Frontiers in Cell and …, 2022 - frontiersin.org
The most common type of cancer in the present-day world affecting modern-day men after
lung cancer is prostate cancer. Prostate cancer remains on the list of top three cancer types …

Hypoxia in tumor microenvironment regulates exosome biogenesis: Molecular mechanisms and translational opportunities

A Kumar, G Deep - Cancer letters, 2020 - Elsevier
Hypoxia is a key feature of solid tumors, associated with disease aggressiveness and poor
outcome. Besides undergoing broad intracellular molecular and metabolic adaptations …

The roles of exosomal proteins: classification, function, and applications

XX Li, LX Yang, C Wang, H Li, DS Shi… - International journal of …, 2023 - mdpi.com
Exosome, a subpopulation of extracellular vesicles, plays diverse roles in various biological
processes. As one of the most abundant components of exosomes, exosomal proteins have …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Influences of age, race, and sex on extracellular vesicle characteristics

NN Hooten, AM Byappanahalli, M Vannoy… - …, 2022 - pmc.ncbi.nlm.nih.gov
Recent attention has focused on the use of extracellular vesicles (EVs) as biological
indicators of health and disease. These small, nano-sized membrane bound vesicles are …

Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics

H Chen, B Pang, C Zhou, M Han, J Gong, Y Li… - Journal of …, 2023 - Springer
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are
insufficient. The hidden onset and poor efficacy of traditional therapies against metastatic …

[HTML][HTML] 8-Hydroxy-2-Deoxyguanosine and 8-Iso-prostaglandin F2α: putative biomarkers to assess oxidative stress damage following Robot-assisted radical …

A Di Minno, A Aveta, M Gelzo, L Tripodi… - Journal of Clinical …, 2022 - mdpi.com
Objective: Prostate cancer (PCa) is the most common type of cancer. Biomarkers help
researchers to understand the mechanisms of disease and refine diagnostic panels. We …

Extracellular vesicles in liquid biopsies: potential for disease diagnosis

J Liu, Y Chen, F Pei, C Zeng, Y Yao… - BioMed Research …, 2021 - Wiley Online Library
Liquid biopsy is conducted through minimally invasive or noninvasive procedures, and the
resulting material can be subjected to genomic, proteomic, and lipidomic analyses for early …

[HTML][HTML] Proteomic analysis of exosomes for discovery of protein biomarkers for prostate and bladder cancer

YT Wang, T Shi, S Srivastava, J Kagan, T Liu… - Cancers, 2020 - mdpi.com
Extracellular vesicles (EVs) are released by nearly all cell types as part of normal cell
physiology, transporting biological cargo, including nucleic acids and proteins, across the …