The biofilm matrix: multitasking in a shared space
The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …
comprising a wide variety of extracellular polymeric substances (EPS), such as …
Plasmid transfer by conjugation in Gram-negative bacteria: from the cellular to the community level
Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …
Current challenges and future opportunities of phage therapy
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …
global health might be devastating if novel antibacterial strategies are not quickly …
Mechanisms Underlying Vibrio cholerae Biofilm Formation and Dispersion
Biofilms are a widely observed growth mode in which microbial communities are spatially
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …
Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …
produced by themselves. Many types of microorganisms that are found on living hosts or in …
Secondary effects of antibiotics on microbial biofilms
Biofilms are assemblages of microorganisms attached to each other, or to a surface, and
encased in a protective, self-produced matrix. Such associations are now recognized as the …
encased in a protective, self-produced matrix. Such associations are now recognized as the …
Short-range quorum sensing controls horizontal gene transfer at micron scale in bacterial communities
J van Gestel, T Bareia, B Tenennbaum… - Nature …, 2021 - nature.com
In bacterial communities, cells often communicate by the release and detection of small
diffusible molecules, a process termed quorum-sensing. Signal molecules are thought to …
diffusible molecules, a process termed quorum-sensing. Signal molecules are thought to …
Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae
Biofilm formation is generally recognized as a bacterial defense mechanism against
environmental threats, including antibiotics, bacteriophages, and leukocytes of the human …
environmental threats, including antibiotics, bacteriophages, and leukocytes of the human …
Antibiotic resistance in bacterial communities
Bacteria are single-celled organisms, but the survival of microbial communities relies on
complex dynamics at the molecular, cellular, and ecosystem scales. Antibiotic resistance, in …
complex dynamics at the molecular, cellular, and ecosystem scales. Antibiotic resistance, in …
Advances and opportunities in image analysis of bacterial cells and communities
The cellular morphology and sub-cellular spatial structure critically influence the function of
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …