Nerve growth factor signaling and its contribution to pain

PA Barker, P Mantyh, L Arendt-Nielsen… - Journal of pain …, 2020 - Taylor & Francis
Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation,
and survival of sympathetic and sensory afferent neurons during development. A substantial …

The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

M Fadgyas-Stanculete, AM Buga… - Journal of molecular …, 2014 - Springer
Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal
pain accompanied by altered bowel habits. Although generally considered a functional …

[HTML][HTML] Early life stress impairs synaptic pruning in the develo** hippocampus

KK Dayananda, S Ahmed, D Wang, B Polis… - Brain, behavior, and …, 2023 - Elsevier
Early life adversity impairs normal hippocampal function and connectivity in various
mammalian species, including humans and rodents. According to the 'cumulative model'the …

Proximate and ultimate perspectives on romantic love

A Bode, G Kushnick - Frontiers in psychology, 2021 - frontiersin.org
Romantic love is a phenomenon of immense interest to the general public as well as to
scholars in several disciplines. It is known to be present in almost all human societies and …

Causal relationship between inflammatory cytokines and autoimmune thyroid disease: a bidirectional two-sample Mendelian randomization analysis

Z Yao, F Guo, Y Tan, Y Zhang, Y Geng, G Yang… - Frontiers in …, 2024 - frontiersin.org
Background Autoimmune thyroid disease (AITD) ranks among the most prevalent thyroid
diseases, with inflammatory cytokines playing a decisive role in its pathophysiological …

Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families

B Al-Mubarak, M Abouelhoda, A Omar, H AlDhalaan… - Scientific reports, 2017 - nature.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with genetic
and clinical heterogeneity. The interplay of de novo and inherited rare variants has been …

Cognitive rehabilitation improves ischemic stroke-induced cognitive impairment: role of growth factors

F Farokhi-Sisakht, M Farhoudi… - Journal of Stroke and …, 2019 - Elsevier
Cognitive dysfunction is the most common nonphysical impairment in the stroke survivors.
This impairment has a negative impact on patients' quality of life affects their daily living …

Inflammatory and neurotrophic factor plasma levels are related to epilepsy independently of etiology

MKM Alvim, ME Morita‐Sherman, CL Yasuda… - …, 2021 - Wiley Online Library
Objective Inflammation plays an essential role in epilepsy. Studies indicate that cytokines
and neurotrophic factors can act in neuroexcitability and epileptogenesis. We aimed to …

Is there a causal link between psychological disorders and functional gastrointestinal disorders?

N Koloski, G Holtmann, NJ Talley - Expert Review of …, 2020 - Taylor & Francis
Introduction Psychological distress is associated with functional gastrointestinal disorders
(FGIDs) including irritable bowel syndrome (IBS) and functional dyspepsia (FD) but only …

[HTML][HTML] NGF-dependent neurons and neurobiology of emotions and feelings: lessons from congenital insensitivity to pain with anhidrosis

Y Indo - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
NGF is a well-studied neurotrophic factor, and TrkA is a receptor tyrosine kinase for NGF.
The NGF–TrkA system supports the survival and maintenance of NGF-dependent neurons …