Importance In clinical and research settings worldwide, low-density lipoprotein cholesterol
(LDL-C) is typically estimated using the Friedewald equation. This equation assumes a fixed …

Importance Low-density lipoprotein cholesterol (LDL-C) is typically estimated with the
Friedewald or Martin/Hopkins equation; however, if triglyceride levels are 400 mg/dL or …

The role of the clinical laboratory is evolving to provide more information to clinicians to
assess cardiovascular disease (CVD) risk and target therapy more effectively. Current …

Background High levels of the triglycerides to high-density lipoprotein cholesterol (TG/HDL-
C) ratio are associated with obesity, metabolic syndrome, and insulin resistance. Objectives …

Background: Recent recommendations favoring nonfasting lipid assessment may affect low-
density lipoprotein cholesterol (LDL-C) estimation. The novel method of LDL-C estimation …

High-density lipoprotein (HDL) is astonishingly complex, but the de facto standard for its
measurement has been remarkably simple: total cholesterol content. It is time to prioritize …

Background Cross-sectional studies have found an association between deficiencies in
serum vitamin D, as measured by 25-hydroxyvitamin D (25 [OH] D), and an atherogenic lipid …

Background: Alternatives to the Friedewald low-density lipoprotein cholesterol (LDL-C)
equation have been proposed. Objective: To compare the accuracy of available LDL-C …

Aims Lipids are central in the development of cardiovascular disease, and the present study
aimed to characterize variation in lipid profiles across different countries to improve …

Background Accurate estimation of low-density lipoprotein cholesterol (LDL-C) is important
for guiding cholesterol-lowering therapy. Different methods currently exist to estimate LDL-C …