The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Zwitterionic hydrogels exhibit eminent nonfouling and hemocompatibility. Several key
challenges hinder their application as coating materials for blood-contacting biomedical …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

Zwitterionic hydrogels have attracted tremendous interest due to their densely charged
network, ultralow fouling characteristics, and excellent biocompatibility. However, the …

Islet transplantation has poor long-term efficacy because of the lack of extracellular matrix
support and neovascularization; this limits its wide application in diabetes research. In this …

The last decades have witnessed the rapid growth of hydrogel bioelectronics. Traditional
hydrogels face challenges when working under extreme conditions, causing a loss of …

Oral peptide or protein delivery is considered a revolutionary alternative to daily
subcutaneous injection; however, major challenges remain in terms of impediments of the …

The implementation of nanotechnology to develop efficient antimicrobial systems has a
significant impact on the prospects of the biomedical field. Nanogels are soft polymeric …