Natural products with antischistosomal activity
J de Moraes - Future Medicinal Chemistry, 2015 - Taylor & Francis
In recent years, natural product groups have been gaining prominence as possible sources
of new drugs for schistosomiasis. This review attempts to update the antischistosomal …
of new drugs for schistosomiasis. This review attempts to update the antischistosomal …
Computational quantum chemistry, molecular docking, and ADMET predictions of imidazole alkaloids of Pilocarpus microphyllus with schistosomicidal properties
JA Rocha, NCS Rego, BTS Carvalho, FI Silva… - PloS one, 2018 - journals.plos.org
Schistosomiasis affects million people and its control is widely dependent on a single drug,
praziquantel. Computational chemistry has led to the development of new tools that predict …
praziquantel. Computational chemistry has led to the development of new tools that predict …
Anthelmintic Activity In Vivo of Epiisopiloturine against Juvenile and Adult Worms of Schistosoma mansoni
MA Guimaraes, RN de Oliveira… - PLoS neglected …, 2015 - journals.plos.org
Schistosomiasis is a serious disease currently estimated to affect more that 207 million
people worldwide. Due to the intensive use of praziquantel, there is increasing concern …
people worldwide. Due to the intensive use of praziquantel, there is increasing concern …
Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like …
RC Dos Santos, AS Ombredane, JMT Souza… - Food Research …, 2018 - Elsevier
This study investigated a lycopene-rich extract from red guava (LEG) for its chemical
composition using spectrophotometry, mass spectrometry, attenuated total reflectance …
composition using spectrophotometry, mass spectrometry, attenuated total reflectance …
Anthelmintic, Antibacterial and Cytotoxicity Activity of Imidazole Alkaloids from Pilocarpus microphyllus Leaves
Pilocarpus microphyllus Stapf ex Wardlew (Rutaceae), popularly known as jaborandi, is a
plant native to the northern and northeastern macroregions of Brazil. Several alkaloids from …
plant native to the northern and northeastern macroregions of Brazil. Several alkaloids from …
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity
MA Guimarães, RN de Oliveira, RL de Almeida… - PLoS …, 2018 - journals.plos.org
Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently
affecting more than 200 million people. Among the various species of this parasite that infect …
affecting more than 200 million people. Among the various species of this parasite that infect …
Acetylated cashew gum-based nanoparticles for the incorporation of alkaloid epiisopiloturine
J do Amaral Rodrigues, AR de Araújo… - International journal of …, 2019 - Elsevier
The natural alkaloid epiisopiloturine has recently become the focus of study for various
medicinal properties, particularly for its anti-inflammatory and antischistosomal effect. The …
medicinal properties, particularly for its anti-inflammatory and antischistosomal effect. The …
Ruthenium Complexes, an Emerging Class of Leishmanicidal Drug Candidates
SS Braga - Applied Biosciences, 2022 - mdpi.com
This review addresses the search for activity enhancement of leishmanicidal organic
compounds through their coordination chemistry with ruthenium. In an introduction to …
compounds through their coordination chemistry with ruthenium. In an introduction to …
LAPONITE®-pilocarpine hybrid material: experimental and theoretical evaluation of pilocarpine conformation
The intercalation of protonated pilocarpine (Pilo+) into model LAPONITE®(Lap) is here
investigated in order to address its conformational properties upon entrapment. Pilo is an …
investigated in order to address its conformational properties upon entrapment. Pilo is an …
Epiisopiloturine nanoencapsulation improve its oral bioavailability in the treatment of inflammatory bowel diseases
VPA de Almeida, TML da Silva, JJ da Silva Sousa… - Medical …, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) are a group of diseases represented mainly by Crohn's
disease (CD) and ulcerative colitis (UC), whose current treatments are associated with a …
disease (CD) and ulcerative colitis (UC), whose current treatments are associated with a …