Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics

X Feng, A Sureda, S Jafari, Z Memariani… - …, 2019 - pmc.ncbi.nlm.nih.gov
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation: Involvement of vitamin K-dependent processes

P Petsophonsakul, M Furmanik, R Forsythe… - … , and vascular biology, 2019 - ahajournals.org
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

Diabetic cardiovascular disease induced by oxidative stress

Y Kayama, U Raaz, A Jagger, M Adam… - International journal of …, 2015 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among
patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications …

Understanding the pathogenesis of abdominal aortic aneurysms

H Kuivaniemi, EJ Ryer, JR Elmore… - Expert review of …, 2015 - Taylor & Francis
An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …

Trajectories of age-related arterial stiffness in Chinese men and women

Y Lu, R Pechlaner, J Cai, H Yuan, Z Huang… - Journal of the American …, 2020 - jacc.org
Background Arterial stiffening is central in the vascular aging process. Traditionally, vascular
research has focused on atherosclerotic vascular disease, whereas arterial stiffness has not …