Synthesis and applications of mirror-image proteins

K Harrison, AS Mackay, L Kambanis… - Nature Reviews …, 2023 - nature.com
The homochirality of biomolecules in nature, such as DNA, RNA, peptides and proteins, has
played a critical role in establishing and sustaining life on Earth. This chiral bias has also …

The role of antimicrobial peptides in plant immunity

ML Campos, CM de Souza… - Journal of …, 2018 - academic.oup.com
Selective pressure imposed by millions of years of relentless biological attack has led to the
development of an extraordinary array of defense strategies in plants. Among these …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

D‐peptide and d‐protein technology: recent advances, challenges, and opportunities

AJ Lander, Y **, LYP Luk - ChemBioChem, 2023 - Wiley Online Library
Total chemical protein synthesis provides access to entire D‐protein enantiomers enabling
unique applications in molecular biology, structural biology, and bioactive compound …

Plant antimicrobial peptides: state of the art, in silico prediction and perspectives in the omics era

CA Santos-Silva, L Zupin… - … and Biology Insights, 2020 - journals.sagepub.com
Even before the perception or interaction with pathogens, plants rely on constitutively
guardian molecules, often specific to tissue or stage, with further expression after contact …

Novel protein science enabled by total chemical synthesis

SBH Kent - Protein Science, 2019 - Wiley Online Library
Chemical synthesis is a well‐established method for the preparation in the research
laboratory of multiple‐tens‐of‐milligram amounts of correctly folded, high purity protein …

GASA proteins: Review of their functions in plant environmental stress tolerance

MT Bouteraa, W Ben Romdhane, N Baazaoui… - Plants, 2023 - mdpi.com
Gibberellic acid-stimulated Arabidopsis (GASA) gene family is a class of functional cysteine-
rich proteins characterized by an N-terminal signal peptide and a C-terminal-conserved …

Computational tools for exploring sequence databases as a resource for antimicrobial peptides

WF Porto, AS Pires, OL Franco - Biotechnology advances, 2017 - Elsevier
Data mining has been recognized by many researchers as a hot topic in different areas. In
the post-genomic era, the growing number of sequences deposited in databases has been …

Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist

C Zuo, WW Shi, XX Chen, M Glatz, B Riedl… - Science China …, 2019 - Springer
Blockade of the interaction of anaphylatoxin C5a with its receptor C5aR1 has been actively
studied as a potential treatment for many inflammatory diseases; but current C5a …

Food allergens of plant origin

Y Zhang, H Che, C Li, T ** - Foods, 2023 - mdpi.com
This review presents an update on the physical, chemical, and biological properties of food
allergens in plant sources, focusing on the few protein families that contribute to multiple …